Defined by the accumulation of red blood cells into the alveolar space, diffuse alveolar
hemorrhage (DAH) is a severe and potentially fatal medical condition requiring careful …

Basement membrane components are targets of autoimmune attack in diverse diseases that
destroy kidneys, lungs, skin, mucous membranes, joints, and other organs in man. Epitopes …

Chronic allograft nephropathy (CAN) of renal allografts is still the most important cause of
graft loss. A subset of these patients have transplant glomerulopathy (TGP), characterized by …

The respiratory system may be involved in all types of systemic vasculitis with varying
significance and frequency. ANCA-associated vasculitis, including granulomatosis with …

Immune mechanisms play an important role in the pathogenesis of glomerulonephritis (GN),
with autoimmunity being the main underlying pathogenetic process of both primary and …

IL-12 and IFN-γ play key roles in murine lupus and planted antigen models of
glomerulonephritis. However, their roles in renal organ–specific autoimmunity are unknown …

Myeloperoxidase (MPO) anti‐neutrophil cytoplasmic antibodies (ANCA) are often detected
in association with a variety of lung pathologies, the most common being interstitial lung …

Lupus nephritis is one of the most serious manifestations of systemic lupus erythematosus,
and represents one of the criteria implemented to classify systemic lupus erythematosus …

Treatment of glomerulonephritis: Will we ever have options other than steroids and
cytotoxics? Glomerulonephritis refers to a collection of primary renal disorders and those …

The mechanism by which phosphorus levels are maintained in the body was investigated by
analyzing changes in gene expression in the rat kidney following administration of a high …