Crosstalk of inflammatory cytokines within the breast tumor microenvironment

O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Role of leptin in inflammation and vice versa

A Pérez-Pérez, F Sánchez-Jiménez… - International journal of …, 2020 - mdpi.com
Inflammation is an essential immune response for the maintenance of tissue homeostasis. In
a general sense, acute and chronic inflammation are different types of adaptive response …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Obesity, inflammation, and cancer

T Deng, CJ Lyon, S Bergin, MA Caligiuri… - Annual Review of …, 2016 - annualreviews.org
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including cancer, and is increasingly recognized as a growing cause of preventable cancer …

Obesity and cancer: inflammation bridges the two

R Kolb, FS Sutterwala, W Zhang - Current opinion in pharmacology, 2016 - Elsevier
Highlights•Obesity is associated with chronic inflammation and chronic diseases.•Obesity is
associated with increased risk and progression of several cancers.•The mechanism by …

Obesity and breast cancer: role of leptin

F Sánchez-Jiménez, A Pérez-Pérez… - Frontiers in …, 2019 - frontiersin.org
Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …

Obesity and cancer pathogenesis

NA Berger - Annals of the New York Academy of Sciences, 2014 - Wiley Online Library
Overweight and obesity have reached pandemic levels on a worldwide basis and are
associated with increased risk and worse prognosis for many but not all malignancies …

Unraveling the role of leptin in liver function and its relationship with liver diseases

M Martínez-Uña, Y López-Mancheño… - International journal of …, 2020 - mdpi.com
Since its discovery twenty-five years ago, the fat-derived hormone leptin has provided a
revolutionary framework for studying the physiological role of adipose tissue as an …

Molecular links between central obesity and breast cancer

AA Zimta, AB Tigu, M Muntean, D Cenariu… - International journal of …, 2019 - mdpi.com
Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …

Linkage between obesity leptin and breast cancer

MF Atoum, F Alzoughool… - Breast Cancer: Basic …, 2020 - journals.sagepub.com
Many cancers might be influenced by obesity, including breast cancer, the leading cause of
cancer death among women. Obesity is a complex state associated with multiple …