SARS-CoV-2 has caused up to 127 million cases of COVID-19. Approximately 5% of COVID-
19 patients develop severe illness, and approximately 40% of those with severe illness …

Sepsis is a life-threatening disorder disease defined as infection-induced dysregulated
immune responses and multiple organ dysfunction. The imbalance between …

Objective To date, there are no studies regarding the lactylation profile and its role in
critically ill patients. Thus, we aimed to examine expression of histone H3 lysine 18 (H3K18) …

Abstract Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied
inducible cell adhesion molecules which is responsible for several immune functions like T …

Sepsis is a major health problem worldwide. As the number of sepsis cases increases, so
does the number of sepsis survivors who suffer from" post-sepsis syndrome" after hospital …

Background Sepsis is an increasingly significant challenge throughout the world as one of
the major causes of patient morbidity and mortality. Central to the host immunologic …

High-density lipoproteins (HDLs) are a class of blood particles, principally involved in
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …

Sepsis is characterized by an initial hyperinflammatory response, with intense cell activation
and cytokine storm. In parallel, a prolonged compensatory anti-inflammatory response …

Background: Sepsis coagulopathy or disseminated intravascular coagulation (DIC) mainly
due to progressive endothelial disruption and damage. The glycocalyx is expressed on the …

Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host
response to infection. Despite treatment being in line with current guidelines, mortality …