The epigenetics of migraine
F Zobdeh, II Eremenko, MA Akan, VV Tarasov… - International Journal of …, 2023 - mdpi.com
Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …
High risk-human papillomavirus in HNSCC: Present and future challenges for epigenetic therapies
L Ghiani, S Chiocca - International Journal of Molecular Sciences, 2022 - mdpi.com
Head and Neck Squamous Cell Carcinoma (HNSCC) is a highly heterogeneous group of
tumors characterized by an incidence of 650,000 new cases and 350,000 deaths per year …
tumors characterized by an incidence of 650,000 new cases and 350,000 deaths per year …
[HTML][HTML] Effects of Environmental Factors and Epigenetic on Health and the Development of Diseases
M Farrokhi, F Taheri, E Karami, R Khorram… - Kindle, 2023 - preferpub.org
The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …
are complex and interconnected. Environmental factors encompass external influences like …
Targeting cancer epigenetic pathways with small-molecule compounds: therapeutic efficacy and combination therapies
Y Wang, Q Xie, H Tan, M Liao, S Zhu, LL Zheng… - Pharmacological …, 2021 - Elsevier
Epigenetics mainly refers to covalent modifications to DNA or histones without affecting
genomes, which ultimately lead to phenotypic changes in cells or organisms. Given the …
genomes, which ultimately lead to phenotypic changes in cells or organisms. Given the …
Molecular genetics and targeted therapies for paediatric high-grade glioma
KS Rallis, AM George, AM Wozniak… - Cancer Genomics & …, 2022 - cgp.iiarjournals.org
Brain tumours are the leading cause of paediatric cancer-associated death worldwide. High-
grade glioma (HGG) represents a main cause of paediatric brain tumours and is associated …
grade glioma (HGG) represents a main cause of paediatric brain tumours and is associated …
Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease
G Assante, S Chandrasekaran, S Ng, A Tourna… - Genome medicine, 2022 - Springer
Background The incidence of non-alcoholic fatty liver disease (NAFLD)-associated
hepatocellular carcinoma (HCC) is increasing worldwide, but the steps in precancerous …
hepatocellular carcinoma (HCC) is increasing worldwide, but the steps in precancerous …
Histone acetyltransferase inhibition reverses opacity in rat galactose-induced cataract
M Nagaya, R Yamaoka, F Kanada, T Sawa… - Plos one, 2022 - journals.plos.org
Cataract, a disease that causes opacity of the lens, is the leading cause of blindness
worldwide. Cataracts secondary to diabetes are common, even in young patients, so they …
worldwide. Cataracts secondary to diabetes are common, even in young patients, so they …
Complex cross-talk between EZH2 and miRNAs confers hallmark characteristics and shapes the tumor microenvironment
CRT Hillyar, SS Kanabar, KS Rallis, JS Varghese - Epigenomics, 2022 - Future Medicine
Cancer epigenetic mechanisms support the acquisition of hallmark characteristics during
oncogenesis. EZH2–an important histone methyltransferase that writes histone H3 lysine 27 …
oncogenesis. EZH2–an important histone methyltransferase that writes histone H3 lysine 27 …
[HTML][HTML] Targeting bromodomain and extra-terminal proteins to inhibit neuroblastoma tumorigenesis through regulating MYCN
X Shi, Y Wang, L Zhang, W Zhao, X Dai… - Frontiers in Cell and …, 2022 - frontiersin.org
Bromodomain and extra-terminal domain (BET) family proteins play important roles in
regulating the expression of multiple proto-oncogenes by recognizing acetylation of histones …
regulating the expression of multiple proto-oncogenes by recognizing acetylation of histones …
Epigenetic alterations in canine mammary cancer
BN Borges - Genetics and Molecular Biology, 2022 - SciELO Brasil
In dogs, mammary cancer is the most common tumor type, especially in unspayed females.
As in humans, this type of cancer has spontaneous development and is influenced by …
As in humans, this type of cancer has spontaneous development and is influenced by …