Hydrogels obtained from natural polymers have received widespread attention for their
excellent biocompatible property, nontoxicity, easy gelation, and functionalization …

Nonspecific distribution and uncontrollable release of drugs in conventional drug delivery
systems (CDDSs) have led to the development of smart nanocarrier-based drug delivery …

Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

Cancer is a group of disorders characterized by uncontrolled cell growth that affects around
11 million people each year globally. Nanocarrier-based systems are extensively used in …

Metal− organic frameworks (MOFs) are a novel class of porous hybrid organic− inorganic
materials that have attracted increasing attention over the past decade. MOFs can be used …

Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Until now, enormous smart materials have been engineered with endogenous stimulators
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …

Presently, nanocarriers (NCs) have gained huge attention for their structural ability, good
biocompatibility, and biodegradability. The development of effective NCs with stimuli …

In this study, we reviewed state-of-the-art endogenous-based and exogenous-based stimuli-
responsive drug delivery systems (DDS) for programmed site-specific release to overcome …

Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …