Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

Immunogenic cell death (ICD) is a type of cancer cell death triggered by certain
chemotherapeutic drugs, oncolytic viruses, physicochemical therapies, photodynamic …

The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …

The IL-1 family of cytokines consists of IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, and IL-36γ.
These proteins form four signaling receptor complexes: the IL-1 receptor (IL-1R1 and IL …

Head and neck squamous cell carcinoma (HNSCC) encompass a group of complex entities
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …

Interleukin-1α (IL-1α) is a major alarmin cytokine which triggers and boosts the inflammatory
responses. Since its discovery in the 1940s, the structure and bioactivity of IL-1α has been …

Cancer is the primary cause of death in economically developed countries and the second
leading cause in developing countries. Colorectal cancer (CRC) is the third most common …

Since its introduction, the use of cetuximab in the treatment of head and neck squamous cell
carcinoma (HNSCC) has experienced an evolution. Currently, cetuximab associated with …

Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

Alternol is a naturally occurring compound that exerts antitumor activity in several cancers.
However, whether Alternol induces antitumor immune response remains unknown. In this …