Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …

Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

Objective A global consensus meeting was held to review current evidence and knowledge
gaps and propose collaborative studies on population-wide screening and eradication of …

Abstract Background and Aim Helicobacter pylori (H. pylori) infection rates have been
changing with different populations and geographic areas. We systematically evaluated the …

The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

The last 5 years have seen major shifts in defining whom to test and how to treat
Helicobacter pylori infection. Peptic ulcer has changed from a chronic disease to a one-off …

Gastric adenocarcinoma carries a poor prognosis, in part due to the late stage of diagnosis.
Risk factors include Helicobacter pylori infection, family history of gastric cancer—in …

Background & Aims In 2017, the World Health Organization (WHO) designated
clarithromycin-resistant Helicobacter pylori a high priority for antibiotic research and …

Objective Although mass eradication of Helicobacter pylori has been proposed as a means
to eliminate gastric cancer, its long-term effects remain unclear. Design Mass eradication of …