Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …

Many important events occur at birth. The fetus is suddenly removed from a protected intra-
uterine environment that is aquatic, warm, and nearly sterile, to the dry, cold external world …

Previously, two men were cured of HIV-1 through CCR5Δ32 homozygous (CCR5Δ32/Δ32)
allogeneic adult stem cell transplant. We report the first remission and possible HIV-1 cure in …

Background: Early-onset sepsis, occurring within 72 hours of birth, and late-onset sepsis,
occurring after this time period, present serious risks for neonates. While culture-based …

Infant formulas are an alternative to replace or supplement human milk when breastfeeding
is not possible. The knowledge of human milk's bioactive compounds and their beneficial …

Background Nirsevimab is an extended half-life monoclonal antibody to the respiratory
syncytial virus (RSV) fusion protein that has been developed to protect infants for an entire …

The first 1,000 days in the life of a human being are a vulnerable stage where early stimuli
may program adverse health outcomes in future life. Proper maternal nutrition before and …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Intestinal inflammatory diseases, such as Crohn's disease, ulcerative colitis, and necrotizing
enterocolitis, are becoming increasingly prevalent. While knowledge of the pathogenesis of …

Objective To review the different causes of secondary immunodeficiencies and provide
clinicians with an updated overview of potential factors that contribute to immunodeficiency …