Cardiac intercellular communication: are myocytes and fibroblasts fair-weather friends?
ML Martin, BC Blaxall - Journal of cardiovascular translational research, 2012 - Springer
The cardiac fibroblast (CF) has historically been thought of as a quiescent cell of the heart,
passively maintaining the extracellular environment for the cardiomyocytes (CM), the …
passively maintaining the extracellular environment for the cardiomyocytes (CM), the …
Transcription factor NF-κB is necessary for up-regulation of type 1 angiotensin II receptor mRNA in rat cardiac fibroblasts treated with tumor necrosis factor-α or …
RT Cowling, D Gurantz, JF Peng, WH Dillmann… - Journal of Biological …, 2002 - ASBMB
Tumor necrosis factor-α (TNF-α) and interleukin-1β up-regulate type 1 angiotensin II
receptor (AT 1) mRNA and protein in cultured neonatal rat cardiac fibroblasts. The use of …
receptor (AT 1) mRNA and protein in cultured neonatal rat cardiac fibroblasts. The use of …
Inflammatory response post-myocardial infarction and reperfusion: a new therapeutic target?
RF Bonvini, T Hendiri… - European Heart Journal …, 2005 - academic.oup.com
Inflammation is a cornerstone of the post-myocardial infarction healing process. However,
an exuberant systemic as well as loco-regional inflammatory response may have a direct …
an exuberant systemic as well as loco-regional inflammatory response may have a direct …
Simvastatin inhibits TNFα-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and-independent mechanisms
NA Turner, PK Aley, KT Hall, P Warburton… - Journal of molecular and …, 2007 - Elsevier
Statins can reduce adverse myocardial remodeling independently of their cholesterol-
lowering ability. We have previously reported that simvastatin inhibits tumor necrosis factor-α …
lowering ability. We have previously reported that simvastatin inhibits tumor necrosis factor-α …
Administration of a tumor necrosis factor inhibitor at the time of myocardial infarction attenuates subsequent ventricular remodeling
MF Berry, YJ Woo, TJ Pirolli, LT Bish, MA Moise… - The Journal of heart and …, 2004 - Elsevier
BACKGROUND: Tumor necrosis factor (TNF) causes myocardial extracellular matrix
remodeling and fibrosis in myocardial infarction and chronic heart failure models. Pre …
remodeling and fibrosis in myocardial infarction and chronic heart failure models. Pre …
TNF-α antibodies are as effective as ischemic preconditioning in reducing infarct size in rabbits
S Belosjorow, I Bolle, A Duschin… - American Journal of …, 2003 - journals.physiology.org
Pretreatment with tumor necrosis factor-α (TNF-α) antibodies abolishes myocardial infarct
size reduction by late ischemic preconditioning (IP). Whether or not TNF-α is also important …
size reduction by late ischemic preconditioning (IP). Whether or not TNF-α is also important …
The role of CEA-related cell adhesion molecule-1 (CEACAM1) in vascular homeostasis
Carcinoembryonic antigen (CEA)-related cell adhesion molecules belong to the
immunoglobulin superfamily, are expressed in a broad spectrum of tissues and cell types …
immunoglobulin superfamily, are expressed in a broad spectrum of tissues and cell types …
Methotrexate carried in lipid core nanoparticles reduces myocardial infarction size and improves cardiac function in rats
RC Maranhão, MC Guido, AD de Lima… - International journal …, 2017 - Taylor & Francis
Purpose Acute myocardial infarction (MI) is accompanied by myocardial inflammation,
fibrosis, and ventricular remodeling that, when excessive or not properly regulated, may lead …
fibrosis, and ventricular remodeling that, when excessive or not properly regulated, may lead …
Myocardial heat shock proteins during the development of heart failure
K Tanonaka, H Yoshida, W Toga, K Furuhama… - Biochemical and …, 2001 - Elsevier
When cardiomyocytes are exposed to stresses, production of heat shock proteins (HSPs) in
the cells is enhanced. Such increase in cellular HSP production is considered to bring about …
the cells is enhanced. Such increase in cellular HSP production is considered to bring about …
Plasma von Willebrand factor level is transiently elevated in a rat model of acute myocardial infarction
Y Li, L Li, F Dong, L Guo, Y Hou… - Experimental and …, 2015 - spandidos-publications.com
The von Willebrand factor (vWF) is a plasma glycoprotein that plays an essential role in
hemostasis by supporting platelet adhesion and thrombus formation in response to vascular …
hemostasis by supporting platelet adhesion and thrombus formation in response to vascular …