The cardiac fibroblast (CF) has historically been thought of as a quiescent cell of the heart,
passively maintaining the extracellular environment for the cardiomyocytes (CM), the …

Tumor necrosis factor-α (TNF-α) and interleukin-1β up-regulate type 1 angiotensin II
receptor (AT 1) mRNA and protein in cultured neonatal rat cardiac fibroblasts. The use of …

Inflammation is a cornerstone of the post-myocardial infarction healing process. However,
an exuberant systemic as well as loco-regional inflammatory response may have a direct …

Statins can reduce adverse myocardial remodeling independently of their cholesterol-
lowering ability. We have previously reported that simvastatin inhibits tumor necrosis factor-α …

BACKGROUND: Tumor necrosis factor (TNF) causes myocardial extracellular matrix
remodeling and fibrosis in myocardial infarction and chronic heart failure models. Pre …

Pretreatment with tumor necrosis factor-α (TNF-α) antibodies abolishes myocardial infarct
size reduction by late ischemic preconditioning (IP). Whether or not TNF-α is also important …

Carcinoembryonic antigen (CEA)-related cell adhesion molecules belong to the
immunoglobulin superfamily, are expressed in a broad spectrum of tissues and cell types …

Purpose Acute myocardial infarction (MI) is accompanied by myocardial inflammation,
fibrosis, and ventricular remodeling that, when excessive or not properly regulated, may lead …

When cardiomyocytes are exposed to stresses, production of heat shock proteins (HSPs) in
the cells is enhanced. Such increase in cellular HSP production is considered to bring about …

The von Willebrand factor (vWF) is a plasma glycoprotein that plays an essential role in
hemostasis by supporting platelet adhesion and thrombus formation in response to vascular …