Progesterone receptor membrane component 1 (PGRMC1) is a multi-functional protein with
a heme-binding moiety related to that of cytochrome b 5, which is a putative progesterone …

Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a heme-binding
protein that has been implicated in a wide range of cell and tissue functions, including …

Background PGRMC1 (progesterone receptor membrane component 1) is a highly
conserved heme binding protein, which is overexpressed especially in hormone receptor …

Simple Summary Ovarian and endometrial cancers occur frequently and can be lethal.
Recently, progesterone receptor membrane component (PGRMC) 1 and PGRMC2 have …

Simple Summary Combined menopausal hormone therapy is associated with increased
breast cancer risk in postmenopausal women. In our previous studies, progesterone …

Introduction Patients with various advanced cancers devoid of nuclear progesterone
receptors (nPR) have demonstrated increased quality and length of life when treated with …

Progesterone receptor membrane component (PGRMC) proteins play important roles in
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …

Non-alcoholic fatty liver disease (NAFLD) results from triglyceride accumulation within the
liver and some of them advances to non-alcoholic steatohepatitis (NASH). It is important to …

An inappropriate response to progestogens in the human endometrium can result in fertility
issues and jeopardize progestin-based treatments against pathologies such as …

PGRMC1 is a protein from the MAPR family with a range of cellular functions. PGRMC1 has
been described to play a role in fertility, neuroprotection, steroidogenesis, membrane …