[HTML][HTML] Thrombotic risk in patients with primary immune thrombocytopenia is only mildly increased and explained by personal and treatment‐related risk factors

M Ruggeri, A Tosetto, F Palandri, N Polverelli… - Journal of Thrombosis …, 2014 - Elsevier
Background An increased risk of thrombosis has been reported in primary immune
thrombocytopenia (ITP) and with the use of thrombopoietin (TPO) receptor agonists, on the …

A critical appraisal of the evidence for the role of splenectomy in adults and children with ITP

F Rodeghiero - British journal of haematology, 2018 - Wiley Online Library
In primary chronic immune thrombocytopenia, long‐term response to splenectomy, with 60%
of patients enjoying a treatment‐free life, is higher when compared with rituximab and …

Immune thrombocytopenia

J Bussel, N Cooper, R Boccia, F Zaja… - Expert Review of …, 2021 - Taylor & Francis
Introduction Primary immune thrombocytopenia (ITP) is an autoimmune disorder
characterized by a low platelet count (< 100× 109/L) with an increased risk of bleeding …

Refractory primary immune thrombocytopenia (ITP): current clinical challenges and therapeutic perspectives

N Vianelli, G Auteri, F Buccisano, V Carrai… - Annals of …, 2022 - Springer
Chronic primary immune thrombocytopenia (ITP) can today benefit from multiple therapeutic
approaches with proven clinical efficacy, including rituximab, thrombopoietin receptor …

Chinese guidelines for treatment of adult primary immune thrombocytopenia

X Liu, X Bai, F Chen, Y Cheng, K Dai, M Fang… - International journal of …, 2018 - Springer
Primary immune thrombocytopenia (ITP) is a bleeding disorder commonly encountered in
clinical practice. The International Working Group (IWG) on ITP has published several …

[HTML][HTML] Rituximab and three dexamethasone cycles provide responses similar to splenectomy in women and those with immune thrombocytopenia of less than two …

JB Bussel, CS Lee, C Seery, AA Imahiyerobo… - …, 2014 - ncbi.nlm.nih.gov
Adults with newly diagnosed or persistent immunothrombocytopenia frequently relapse
upon tapering steroids; adults and children with chronic disease have an even lower …

Characteristics, outcome, and response to therapy of multirefractory chronic immune thrombocytopenia

M Mahévas, M Gerfaud-Valentin… - Blood, The Journal …, 2016 - ashpublications.org
Refractory immune thrombocytopenia (ITP) was previously defined as lack of a minimum
response to splenectomy and the requirement for long-term treatment to reduce the risk of …

[HTML][HTML] Bacterial infections following splenectomy for malignant and nonmalignant hematologic diseases

G Leone, E Pizzigallo - Mediterranean journal of hematology and …, 2015 - ncbi.nlm.nih.gov
Splenectomy, while often necessary in otherwise healthy patients after major trauma, finds
its primary indication for patients with underlying malignant or nonmalignant hematologic …

[PDF][PDF] 立足中国实际的原发免疫性血小板减少症诊治——2020 版成人原发免疫性血小板减少症诊断与治疗中国指南解读

侯明, 刘新光 - 临床血液学杂志, 2021 - lcxyen.whuhzzs.com
专家简介: 侯明, 山东大学齐鲁医院肿瘤中心主任, 血液科主任, 山东省血液免疫重点实验室主任,
泰山学者, 山东大学二级教授, 博士生导师. ITP 国际工作组指南制定专家组成员, ASH 资深会员 …

How I treat primary ITP in adult patients who are unresponsive to or dependent on corticosteroid treatment

W Ghanima, T Gernsheimer… - Blood, The Journal of the …, 2021 - ashpublications.org
Approximately 80% of adult patients with immune thrombocytopenia (ITP) have treatment
failure with corticosteroids or become dependent on them and require second-line therapy …