Diabetic kidney disease (DKD) is becoming the leading cause of chronic kidney disease,
especially in the industrialized world. Despite mounting evidence has demonstrated that …

Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. Increasing
evidence has suggested that inflammation is a key microenvironment involved in the …

Chronic kidney disease (CKD) is a public health problem driven by myofibroblast
accumulation, leading to interstitial fibrosis. Heterogeneity is a recently recognized …

Background Diabetic nephropathy (DN) is one of the most common diabetic complications,
which has become the primary cause of end-stage renal disease (ESRD) globally …

Although glomerular endothelial dysfunction is well recognized as contributing to the
pathogenesis of diabetic kidney disease (DKD), the molecular pathways contributing to DKD …

Numerous studies have proven the critical role of macrophages in the renal fibrosis process.
Notably, G Protein-coupled Estrogen Receptor 1 (GPER1), a novel estrogen receptor, has …

Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent
complication of diabetes and obesity, and yet to date, treatments to halt its progression are …

Background Macrophages are considered an essential source of inflammatory cytokines,
which play a pivotal role in the development of diabetes and its sequent complications …

Background Diabetic kidney disease (DKD) is a common complication of diabetes that is
clinically characterized by progressive albuminuria due to glomerular destruction. The …

Diabetic kidney disease (DKD) is characterized by macrophage infiltration, which requires
further investigation. This study aims to identify immune-related genes (IRGs) in …