Ca2+ channel subunit α 1D promotes proliferation and migration of endometrial cancer cells mediated by 17β‐estradiol via the G protein‐coupled estrogen receptor
J Hao, X Bao, B Jin, X Wang, Z Mao, X Li… - The FASEB …, 2015 - Wiley Online Library
Calcium and calcium channels are closely related to the estrogen‐induced nongenomic
effect of endometrial carcinoma, but the specific role of calcium channels is unknown. This …
effect of endometrial carcinoma, but the specific role of calcium channels is unknown. This …
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels
L Ferron, V Capuano, Y Ruchon, E Deroubaix… - Circulation …, 2003 - Am Heart Assoc
Recent studies indicate that cardiac T-type Ca2+ current (I CaT) reappears in hypertrophied
ventricular cells. The aim of this study was to investigate the role of angiotensin II (Ang II), a …
ventricular cells. The aim of this study was to investigate the role of angiotensin II (Ang II), a …
[HTML][HTML] Ion channels as therapeutic targets in high grade gliomas
M Griffin, R Khan, S Basu, S Smith - Cancers, 2020 - mdpi.com
Simple Summary Glioblastoma multiforme is an aggressive grade IV lethal brain tumour with
a median survival of 14 months. Despite surgery to remove the tumour, and subsequent …
a median survival of 14 months. Despite surgery to remove the tumour, and subsequent …
Variation of T-type calcium channel protein expression affects cell division of cultured tumor cells
A Panner, LL Cribbs, GM Zainelli, TC Origitano… - Cell calcium, 2005 - Elsevier
In this study we investigated the T-type calcium channel and its involvement in the cell
division of U87MG cultured glioma cells and N1E-115 neuroblastoma cells. Using Western …
division of U87MG cultured glioma cells and N1E-115 neuroblastoma cells. Using Western …
Intelligent gold nanoparticles for synergistic tumor treatment via intracellular Ca2+ regulation and resulting on-demand photothermal therapy
X Guo, Q Su, T Liu, X He, P Yuan, R Tian, B Li… - Chemical Engineering …, 2022 - Elsevier
Designing therapeutics to utilize and manipulate the aberrant high concentration of Ca 2+ in
tumor cells would be a promising approach for effective tumor therapy. Herein, we fabricated …
tumor cells would be a promising approach for effective tumor therapy. Herein, we fabricated …
[HTML][HTML] Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β
Large tumors exhibit high interstitial pressure heightened by growth against the constraining
stroma. Such pressures could stimulate tumor proliferation via a mechanosensitive ion …
stroma. Such pressures could stimulate tumor proliferation via a mechanosensitive ion …
[HTML][HTML] Deepening the whole transcriptomics of bovine liver cells exposed to AFB1: a spotlight on toll-like receptor 2
S Iori, M Pauletto, I Bassan, F Bonsembiante… - Toxins, 2022 - mdpi.com
Aflatoxin B1 (AFB1) is a food contaminant metabolized mostly in the liver and leading to
hepatic damage. Livestock species are differently susceptible to AFB1, but the underlying …
hepatic damage. Livestock species are differently susceptible to AFB1, but the underlying …
[HTML][HTML] Ovarian cancer: Ion channel and aquaporin expression as novel targets of clinical potential
J Frede, SP Fraser, G Oskay-Özcelik, Y Hong… - European journal of …, 2013 - Elsevier
Ovarian cancer is associated with limited overall survival, due to problems in early detection
and therapy. Membrane ion channels have been proposed to play a significant, concerted …
and therapy. Membrane ion channels have been proposed to play a significant, concerted …
Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells
M Yoshida, K Nosaka, J Yasunaga, I Nishikata… - Blood, 2004 - ashpublications.org
DNA methylation plays critical roles in the development and differentiation of mammalian
cells, and its dysregulation has been implicated in oncogenesis. This study was designed to …
cells, and its dysregulation has been implicated in oncogenesis. This study was designed to …
[HTML][HTML] DNA methylation of channel-related genes in cancers
H Ouadid-Ahidouch, L Rodat-Despoix, F Matifat… - … et Biophysica Acta (BBA …, 2015 - Elsevier
DNA methylation at CpG sites is an epigenetic mechanism that regulates cellular gene
expression. In cancer cells, aberrant methylation is correlated with the abnormalities in …
expression. In cancer cells, aberrant methylation is correlated with the abnormalities in …