Regulation of Ca2+ channels has been implicated in the progression of tumor cells. We
report here that T-type Ca2+ channel expression in human ovarian cancer tissues is greatly …

Epithelial tumor cells express T-type Ca2+ channels, which are thought to promote cell
proliferation. This study investigated the cellular response to T-type Ca2+ channel inhibition …

The expression of voltage‐gated calcium channels (VGCCs) has not been reported
previously in melanoma cells in spite of increasing evidence of a role of VGCCs in …

The mammary gland is subjected to extensive calcium loads during lactation to support the
requirements of milk calcium enrichment. Despite the indispensable nature of calcium …

Over the past years, studies have described that users of antipsychotics are less likely to
develop cancer than the population in general due to cytotoxic properties of this class of …

We investigated the regulation of T-type channels by Rho-associated kinase (ROCK).
Activation of ROCK via the endogenous ligand lysophosphatidic acid (LPA) reversibly …

Global efforts invested in the prevention and treatment of cancer need to be repositioned to
develop safe, effective, and economic anticancer therapeutics by adopting rational …

Aims Despite the advanced cancer treatments, there is increased resistance to
chemotherapy and subsequent mortality. In lack of reliable data in monolayer cultures and …

Milk nutrients are secreted by epithelial cells in the alveoli of the mammary gland by several
complex and highly coordinated systems. Many of these nutrients are transported from the …

Purpose The purpose of this review article is to discuss the potential of T-type voltage gated
calcium channels (VGCCs) as drug targets in breast cancer. Summary Breast cancer …