Immunogenic cell stress and death
Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …
immunological correlates of cellular stress and death. In the absence of reactive antigenic …
Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors
The development of combination immunotherapy based on the mediation of regulatory
mechanisms of the tumor immune microenvironment (TIME) is promising. However, a deep …
mechanisms of the tumor immune microenvironment (TIME) is promising. However, a deep …
COVID-19 and cancer: a comprehensive review
Abstract Purpose of Review The outbreak of the novel coronavirus disease 2019 (COVID-
19) has emerged to be the biggest global health threat worldwide, which has now infected …
19) has emerged to be the biggest global health threat worldwide, which has now infected …
Combining antibody-drug conjugates with immunotherapy in solid tumors: current landscape and future perspectives
Antibody-drug conjugates (ADCs) and immunotherapy have prompted a revolution in the
treatment of cancer. However, only a limited fraction of patients obtained a long-term benefit; …
treatment of cancer. However, only a limited fraction of patients obtained a long-term benefit; …
The expanding role for small molecules in immuno-oncology
R Offringa, L Kötzner, B Huck, K Urbahns - Nature Reviews Drug …, 2022 - nature.com
The advent of immune checkpoint inhibition (ICI) using antibodies against PD1 and its
ligand PDL1 has prompted substantial efforts to develop complementary drugs. Although …
ligand PDL1 has prompted substantial efforts to develop complementary drugs. Although …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
Hyperprogressive disease during PD-1 blockade in patients with advanced hepatocellular carcinoma
Background & Aims Programmed cell death-1 (PD-1) inhibitor treatment can cause
hyperprogressive disease (HPD), but the incidence, outcome, and predictive factors of HPD …
hyperprogressive disease (HPD), but the incidence, outcome, and predictive factors of HPD …
Immunotherapy approaches for breast cancer patients in 2023
Immunotherapy, particularly agents targeting the immunoregulatory PD-1/PD-L1 axis,
harnesses the power of the immune system to treat cancer, with unique potential for a …
harnesses the power of the immune system to treat cancer, with unique potential for a …
The immuno-oncological challenge of COVID-19
L Derosa, C Melenotte, F Griscelli, B Gachot… - Nature Cancer, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) and its causative virus, SARS-CoV-2, pose
considerable challenges for the management of oncology patients. COVID-19 presents as a …
considerable challenges for the management of oncology patients. COVID-19 presents as a …
[HTML][HTML] Evaluation of COVID-19 vaccine response in patients with cancer: An interim analysis
S Tran, TH Truong, A Narendran - European journal of cancer, 2021 - Elsevier
Background Efficacy and safety data of COVID-19 vaccines among cancer populations have
been limited; however, preliminary data from recent studies have emerged regarding their …
been limited; however, preliminary data from recent studies have emerged regarding their …