Objective: Workers at a beryllium ceramics plant were tested for beryllium sensitization and
disease in 1998 to determine whether the plant-wide prevalence of sensitization and …

Beryllium exposure can cause a granulomatous lung disease in workers who develop a
lymphocyte-mediated sensitization to the metal. Workers in diverse industries are at risk …

A glutamic acid at residue 69 (Glu 69) in the HLA-DPB1 gene (Glu 69) is associated with
chronic beryllium disease (CBD) and possibly beryllium sensitization (BeS). This study …

Chronic beryllium disease results from beryllium exposure in the workplace and is
characterized by CD4+ T cell-mediated inflammation in the lung. Susceptibility to this …

Pulmonary sarcoidosis and chronic beryllium disease (CBD) are inflammatory
granulomatous lung diseases defined by the presence of non-caseating granulomas in the …

The purpose of this review is to describe the present state of knowledge regarding host
susceptibility factors that may determine the occurrence, development and severity of …

Chronic beryllium disease (CBD) is a hypersensitivity granulomatosis characterized by
beryllium hypersensitivity (BH) and mediated by CD4+ T cells. However, all individuals with …

Single-nucleotide polymorphisms (SNPs) are the most abundant type of human genetic
variation. These variable sites are present at high density in the genome, making them …

Sarcoidosis is a multigenic and multifactorial disease. Predisposing genes have been
identified and fast progress in molecular technologies including systematic genome-wide …

Chronic beryllium (Be) disease is a granulomatous lung disorder that results from Be
exposure in a genetically susceptible host. The disease is characterized by the …