COVID-19 vaccine development and a potential nanomaterial path forward

MD Shin, S Shukla, YH Chung, V Beiss… - Nature …, 2020 - nature.com
The COVID-19 pandemic has infected millions of people with no clear signs of abatement
owing to the high prevalence, long incubation period and lack of established treatments or …

Non-viral COVID-19 vaccine delivery systems

KS Park, X Sun, ME Aikins, JJ Moon - Advanced drug delivery reviews, 2021 - Elsevier
The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …

The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Polymeric nanoparticle vaccines to combat emerging and pandemic threats

D Wibowo, SHT Jorritsma, ZJ Gonzaga, B Evert… - Biomaterials, 2021 - Elsevier
Subunit vaccines are more advantageous than live attenuated vaccines in terms of safety
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …

[HTML][HTML] Biomarkers of COVID-19 and technologies to combat SARS-CoV-2

L Zhang, H Guo - Advances in Biomarker Sciences and Technology, 2020 - Elsevier
Due to the unprecedented public health crisis caused by COVID-19, our first contribution to
the newly launching journal, Advances in Biomarker Sciences and Technology, has abruptly …

Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems

M Shi, KJ McHugh - Advanced Drug Delivery Reviews, 2023 - Elsevier
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Thermostable vaccines: An innovative concept in vaccine development

R Kumar, V Srivastava, P Baindara… - Expert Review of …, 2022 - Taylor & Francis
Introduction Vaccines represent he most common and safer ways of combating infectious
diseases. Loss of potency owing to thermal denaturation or degradation of almost all the …

Intranasal drug delivery for treatment of Alzheimer's disease

LC Fonseca, JA Lopes, J Vieira, C Viegas… - Drug Delivery and …, 2021 - Springer
The Alzheimer's disease is a neurodegenerative condition with severe consequences
interfering with patient quality of life. It is characterized as a progressive and irreversible …

Nanotechnology against COVID-19: Immunization, diagnostic and therapeutic studies

A Hasanzadeh, M Alamdaran, S Ahmadi… - Journal of Controlled …, 2021 - Elsevier
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early
2020 soon led to the global pandemic of Coronavirus Disease 2019 (COVID-19). Since …

Orodispersible films–recent developments and new applications in drug delivery and therapy

B Morath, S Sauer, M Zaradzki, AH Wagner - Biochemical Pharmacology, 2022 - Elsevier
Orodispersible films (ODF) are innovative drug formulations that introduce a promising
approach to pharmacotherapy. They represent single-or multi-layer polymer films that show …