Current trends and challenges in point-of-care urinalysis of biomarkers in trace amounts

S Yeasmin, G Ammanath, A Onder, E Yan… - TrAC Trends in …, 2022 - Elsevier
Urinalysis enables non-invasive point-of-care (POC) testing of numerous biomarkers at their
physiological and elevated levels, obviating the need for sophisticated equipment or trained …

Microfluidics‐implemented biochemical assays: from the perspective of readout

W Chen, F Shao, Y Xianyu - Small, 2020 - Wiley Online Library
Over the past decades, microfluidics has emerged as an increasingly important tool to
perform biochemical assays for diagnosis and healthcare. The precise fluid control and …

Colorimetric and fluorescent dual-mode immunoassay based on plasmon-enhanced fluorescence of polymer dots for detection of PSA in whole blood

PY You, FC Li, MH Liu, YH Chan - ACS applied materials & …, 2019 - ACS Publications
Although enormous efforts have been devoted to the development of new types of
fluorometric immunochromatographic test strip (ICTS) with improved sensitivity over the past …

Hydrogel microneedle-assisted assay integrating aptamer probes and fluorescence detection for reagentless biomarker quantification

H Zheng, A GhavamiNejad, P GhavamiNejad… - ACS …, 2022 - ACS Publications
Analyzing interstitial fluid (ISF) via microneedle (MN) devices enables patient health
monitoring in a minimally invasive manner and in point-of-care settings. However, most MN …

Multiplexed detection of tumor markers with multicolor polymer dot-based immunochromatography test strip

CC Fang, CC Chou, YQ Yang, T Wei-Kai… - Analytical …, 2018 - ACS Publications
There have been ongoing efforts to develop more sensitive and fast quantitative screening
of cancer markers by use of fluorometric immunochromatographic test strips (ICTS) since the …

Microfluidic-integrated multicolor immunosensor for visual detection of HIV-1 p24 antigen with the naked eye

D Liu, Y Zhang, M Zhu, Z Yu, X Ma, Y Song… - Analytical …, 2020 - ACS Publications
Here, a fully integrated multicolor immunosensor was developed for sensitive and reliable
semiquantitative analysis of HIV-1 p24, which integrates the multistep reactions of …

Hand-powered centrifugal microfluidic platform inspired by the spinning top for sample-to-answer diagnostics of nucleic acids

L Zhang, F Tian, C Liu, Q Feng, T Ma, Z Zhao, T Li… - Lab on a Chip, 2018 - pubs.rsc.org
Point-of-care (POC), sample-to-answer and electricity-free nucleic acid diagnostic tools are
vital for health care and disease control in resource-limited settings where centralized …

FRET-created traffic light immunoassay based on polymer dots for PSA detection

YQ Yang, YC Yang, MH Liu, YH Chan - Analytical chemistry, 2019 - ACS Publications
There have been enormous efforts for developing the next generations of fluorometric lateral
flow immunochromatographic strip (ICTS) owing to the great advances in fluorescent …

[HTML][HTML] Cannabis detection with solid sensors and paper-based immunoassays by conjugating antibodies to nanocellulose

K Solin, M Vuoriluoto, A Khakalo, T Tammelin - Carbohydrate polymers, 2023 - Elsevier
Highly sensitive and specific diagnostics for cannabis usage are essential for rapid on-site
screening for illicit drug usage. To improve the sensitivity of THC immunoassays, a proper …

Naked-eye based point-of-care detection of E. coli O157: H7 by a signal-amplified microfluidic aptasensor

T Li, G Ou, X Chen, Z Li, R Hu, Y Li, Y Yang, M Liu - Analytica Chimica Acta, 2020 - Elsevier
Fast and sensitive detection of E. coli O157: H7 is significantly essential for clinical
management as well as for transmission prevention during disease outbreaks. Though …