Non-coding RNA networks in cancer

E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

[HTML][HTML] Regulation of the master regulator FOXM1 in cancer

GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …

[HTML][HTML] Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

[HTML][HTML] LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells

W Li, X Dong, C He, G Tan, Z Li, B Zhai, J Feng… - Journal of Experimental …, 2019 - Springer
Background Acquired resistance to sorafenib greatly limits its therapeutic efficiency in the
treatment of hepatocellular carcinoma (HCC). Increasing evidence indicates that long …

[HTML][HTML] Circular RNAs in cancer: limitations in functional studies and diagnostic potential

F Li, Q Yang, AT He, BB Yang - Seminars in cancer biology, 2021 - Elsevier
Circular RNAs (circRNAs) are a large class of noncoding RNAs, generated from a process
called back-splicing, that possess critical regulatory functions in many cellular events. A …

[HTML][HTML] An emerging class of long non-coding RNA with oncogenic role arises from the snoRNA host genes

AA Zimta, AB Tigu, C Braicu, C Stefan, C Ionescu… - Frontiers in …, 2020 - frontiersin.org
The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which
are reported in many studies as being overexpressed in various cancers. With very few …

Noncoding RNA as an influential epigenetic modulator with promising roles in cancer therapeutics

L Roy, O Chatterjee, D Bose, A Roy, S Chatterjee - Drug Discovery Today, 2023 - Elsevier
The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …

Endothelial dysfunction in diabetes and hypertension: role of microRNAs and long non-coding RNAs

H Zhang, Q Xu, A Thakur, MO Alfred, M Chakraborty… - Life sciences, 2018 - Elsevier
The vascular endothelium acts as a barrier between the blood flow and the inner lining of
the vessel wall, and it functions as a filtering machinery to filter out any unwanted transfer of …

The SNHG1-centered ceRNA network regulates cell cycle and is a potential prognostic biomarker for hepatocellular carcinoma

L Zhou, Q Zhang, H Deng, S Ou, T Liang… - The Tohoku Journal of …, 2022 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) is one of the most common and lethal types of cancer. This
study aimed to identify the expression regulatory network and a prognostic signature of …

[HTML][HTML] New therapeutics in endometriosis: a review of hormonal, non-hormonal, and non-coding RNA treatments

G Brichant, I Laraki, L Henry, C Munaut… - International journal of …, 2021 - mdpi.com
Endometriosis is defined as endometrial-like tissue outside the uterine cavity. It is a chronic
inflammatory estrogen-dependent disease causing pain and infertility in about 10% of …