[HTML][HTML] Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

[HTML][HTML] Cancer-associated fibroblasts: master tumor microenvironment modifiers

K Wright, T Ly, M Kriet, A Czirok, SM Thomas - Cancers, 2023 - mdpi.com
Simple Summary Cancer cells rely on the surrounding environment to grow and spread.
This environment contains structural components, secreted factors, immune cells, and other …

IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis

MR Dhamdhere, CP Gowda, V Singh, Z Liu… - Oncogene, 2023 - nature.com
Neuroblastoma is a highly metastatic cancer, and thus is one of the leading causes of
cancer-related mortalities in pediatric patients. More than 50% of NB cases exhibit 17q21-ter …

Embryo-derive TNF promotes decidualization via fibroblast activation

ST Chen, WW Shi, YQ Lin, ZS Yang, Y Wang, MY Li… - Elife, 2023 - elifesciences.org
Decidualization is a process in which endometrial stromal fibroblasts differentiate into
specialized secretory decidual cells and essential for the successful establishment of …

Cancer‐associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications

KY Wong, AHK Cheung, B Chen… - … journal of cancer, 2022 - Wiley Online Library
Lung cancer is the common and leading cause of cancer death worldwide. The tumor
microenvironment has been recognized to be instrumental in tumorigenesis. To have a deep …

[Retracted] Extracellular Vesicles Derived from Lung Cancer Cells Induce Transformation of Normal Fibroblasts into Lung Cancer‐Associated Fibroblasts and Promote …

X Zhang, Y Zhang, X Qiu, J Cai, Z Yang… - Stem Cells …, 2022 - Wiley Online Library
Human lung cancer (LC) cells A549/H358, normal lung epithelial cells BEAS‐2B, and lung
normal fibroblasts (NFs) were cultured, followed by transfection of H358 cells with HOTAIR …

[HTML][HTML] Extracellular vesicles-ceRNAs as ovarian cancer biomarkers: looking into circRNA-miRNA-mRNA code

G Cammarata, N Barraco, I Giusti, V Gristina, V Dolo… - Cancers, 2022 - mdpi.com
Simple Summary Patients with ovarian cancer have a very poor chance of long-term
survival, usually due to advanced disease at the time of diagnosis. Emerging evidence …

[HTML][HTML] Cancer-associated fibroblasts-derived exosomes from chemoresistant patients regulate cisplatin resistance and angiogenesis by delivering VEGFA in …

Y Shi, H Zhu, H Jiang, H Yue, F Yuan, F Wang - Anti-cancer drugs, 2023 - journals.lww.com
The purpose of this study was to investigate the effect of chemoresistant cancer-associated
fibroblasts (R-CAFs) against cisplatin (DDP) on colorectal cancer (CRC) progression. First …

[HTML][HTML] Cancer three-dimensional spheroids mimic in vivo tumor features, displaying “inner” extracellular vesicles and vasculogenic mimicry

I Giusti, G Poppa, S D'Ascenzo, L Esposito… - International Journal of …, 2022 - mdpi.com
The role of extracellular vesicles (EVs) as mediators of cell-to-cell communication in cancer
progression is widely recognized. In vitro studies are routinely performed on 2D culture …

Extracellular vesicles in neuroblastoma: role in progression, resistance to therapy and diagnostics

MR Dhamdhere, VS Spiegelman - Frontiers in immunology, 2024 - frontiersin.org
Neuroblastoma (NB) is the most common extracranial solid pediatric cancer, and is one of
the leading causes of cancer-related deaths in children. Despite the current multi-modal …