Sarcopenia

AJ Cruz-Jentoft, AA Sayer - The Lancet, 2019 - thelancet.com
Sarcopenia is a progressive and generalised skeletal muscle disorder involving the
accelerated loss of muscle mass and function that is associated with increased adverse …

Sarcopenia, osteoporosis and frailty

E Gielen, J Dupont, M Dejaeger, MR Laurent - Metabolism, 2023 - Elsevier
Muscles and bones are intricately connected tissues displaying marked co-variation during
development, growth, aging, and in many diseases. While the diagnosis and treatment of …

Muscle wasting and sarcopenia in heart failure and beyond: update 2017

J Springer, JI Springer, SD Anker - ESC heart failure, 2017 - Wiley Online Library
Sarcopenia (loss of muscle mass and muscle function) is a strong predictor of frailty,
disability and mortality in older persons and may also occur in obese subjects. The …

[HTML][HTML] Sarcopenia: molecular pathways and potential targets for intervention

J Pascual-Fernández, A Fernández-Montero… - International Journal of …, 2020 - mdpi.com
Aging is associated with sarcopenia. The loss of strength results in decreased muscle mass
and motor function. This process accelerates the progressive muscle deterioration observed …

Understanding of sarcopenia: from definition to therapeutic strategies

JW Kim, R Kim, H Choi, SJ Lee, GU Bae - Archives of pharmacal research, 2021 - Springer
Sarcopenia refers to the gradual loss of skeletal muscle mass and function along with aging
and is a social burden due to growing healthcare cost associated with a super-aging society …

The mechanisms and treatments for sarcopenia: could exosomes be a perspective research strategy in the future?

S Rong, L Wang, Z Peng, Y Liao, D Li… - Journal of cachexia …, 2020 - Wiley Online Library
The age‐related loss of muscle mass and muscle function known as sarcopenia is a primary
contributor to the problems faced by the old people. Sarcopenia has been a major public …

Prevalence and incidence of sarcopenia in the very old: findings from the Newcastle 85+ Study

RM Dodds, A Granic, K Davies… - Journal of cachexia …, 2017 - Wiley Online Library
Introduction Recognition that an older person has sarcopenia is important because this
condition is linked to a range of adverse outcomes. Sarcopenia becomes increasingly …

Skeletal muscle wasting in chronic heart failure

T Suzuki, S Palus, J Springer - ESC heart failure, 2018 - Wiley Online Library
Patients suffering from chronic heart failure (CHF) show an increased prevalence (~ 20% in
elderly CHF patients) of loss of muscle mass and muscle function (ie sarcopenia) compared …

Muscle-bone interactions: From experimental models to the clinic? A critical update

MR Laurent, V Dubois, F Claessens… - Molecular and cellular …, 2016 - Elsevier
Bone is a biomechanical tissue shaped by forces from muscles and gravitation.
Simultaneous bone and muscle decay and dysfunction (osteosarcopenia or sarco …

Age-related bone loss and sarcopenia in men

MR Laurent, L Dedeyne, J Dupont, B Mellaerts… - Maturitas, 2019 - Elsevier
Bone and muscle are required for mobility but they also have endocrine and metabolic
functions. In ageing as well as in many chronic diseases, bone loss and muscle atrophy …