Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …

Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic
feature is persistent itching of the skin. The chronic, relapsing course of the disease …

The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

Allergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence,
particularly in westernized countries. Although a detailed mechanistic explanation for this …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both
after atopic dermatitis (AD) onset. Mechanisms for developing atopic comorbidities after AD …

In humans, many diseases are associated with alterations in gut microbiota, namely
increases or decreases in the abundance of specific bacterial groups. One example is the …

abstract The skin microbiome is a key component of pathogenesis in atopic dermatitis (AD).
The skin of AD patients is characterized by microbial dysbiosis, with a reduction of microbial …

The human skin is colonized by variety of microorganisms which, together with their
genomes and interactions with the host, constitute the human skin microbiome. In recent …