Environmental surveillance complements case-based surveillance of acute flaccid paralysis in polio endgame strategy 2019–2023

P Chen, Y Liu, H Wang, G Liu, X Lin… - Applied and …, 2020 - Am Soc Microbiol
ABSTRACT The Polio Endgame Strategy 2019–2023 has been developed. However, more
effective and efficient surveillance activities should be conducted with the preparedness of …

Temporal phylogeny and molecular characterization of echovirus 30 associated with aseptic meningitis outbreaks in China

X Tian, Z Han, Y He, Q Sun, W Wang, W Xu, H Li… - Virology Journal, 2021 - Springer
Background An outbreak of aseptic meningitis occurred from June to August 2016, in Inner
Mongolia Autonomous Region, China. Methods To determine its epidemiological …

Is it time to switch to a formulation other than the live attenuated poliovirus vaccine to prevent poliomyelitis?

CA Devaux, P Pontarotti, A Levasseur… - Frontiers in Public …, 2024 - frontiersin.org
The polioviruses (PVs) are mainly transmitted by direct contact with an infected person
through the fecal-oral route and respiratory secretions (or more rarely via contaminated …

Eradicating polio: how the world's pediatricians can help stop this crippling illness forever

WA Orenstein, Committee on Infectious Diseases - Pediatrics, 2015 - publications.aap.org
Background Before eradication efforts began, polio was a pervasive viral disease and a
significant cause of disability. Polio is highly contagious and may be caused by 3 serotypes …

[HTML][HTML] Modeling the spread of circulating vaccine-derived poliovirus type 2 outbreaks and interventions: A case study of Nigeria

Y Sun, P Keskinocak, LN Steimle, SD Kovacs… - Vaccine: X, 2024 - Elsevier
Background Despite the successes of the Global Polio Eradication Initiative, substantial
challenges remain in eradicating the poliovirus. The Sabin-strain (live-attenuated) virus in …

CaFÉ: a sensitive, low-cost filtration method for detecting polioviruses and other enteroviruses in residual waters

H Belgasmi, SJ Miles, L Sayyad, K Wong… - Frontiers in …, 2022 - frontiersin.org
Acute flaccid paralysis (AFP) surveillance has been used to identify polio cases and target
vaccination campaigns since the inception of the Global Poliovirus Eradication Initiative …

Highly diverse ribonucleic acid viruses in the viromes of eukaryotic host species in Yunnan province, China

Z Han, J Xiao, Y Song, X Zhao, Q Sun, H Lu… - Frontiers in …, 2022 - frontiersin.org
Background The diversity in currently documented viruses and their morphological
characteristics indicates the need for understanding the evolutionary characteristics of …

Improvement of the qmosRT-PCR Assay and Its Application for the Detection and Quantitation of the Three Serotypes of the Novel Oral Polio Vaccine in Stool Samples

H Manukyan, E Tritama, R Wahid, J Anstadt, J Konz… - Vaccines, 2023 - mdpi.com
Recently, genetically stable novel OPVs (nOPV) were developed by modifying the genomes
of Sabin viruses of conventional OPVs to reduce the risk of reversion to neurovirulence and …

Quantitative RT-PCR assays for quantification of undesirable mutants in the novel type 2 oral poliovirus vaccine

H Manukyan, R Wahid, A Ansari, E Tritama… - Vaccines, 2022 - mdpi.com
Emergence of mutations is an inherent property of RNA viruses with several implications for
their replication, pathogenesis, and evolutionary adaptation. Oral poliovirus vaccine (OPV) …

Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission

M Famulare, W Wong, R Haque… - PLOS Computational …, 2021 - journals.plos.org
Since the global withdrawal of Sabin 2 oral poliovirus vaccine (OPV) from routine
immunization, the Global Polio Eradication Initiative (GPEI) has reported multiple circulating …