[HTML][HTML] Tetrahedral framework nucleic acids for improving wound healing

W Zou, J Lu, L Zhang, D Sun - Journal of Nanobiotechnology, 2024 - Springer
Wounds are one of the most common health issues, and the cost of wound care and healing
has continued to increase over the past decade. In recent years, there has been growing …

[HTML][HTML] Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis

X Xiao, M Chen, Y Zhang, L Li, Y Peng, J Li… - Journal of …, 2022 - Springer
Photodynamic therapy (PDT) has emerged as a promising tumor treatment method via light-
triggered generation of reactive oxygen species (ROS) to kill tumor cells. However, the …

[HTML][HTML] NIR/pH-triggered aptamer-functionalized DNA origami nanovehicle for imaging-guided chemo-phototherapy

M Li, G Yang, Y Zheng, J Lv, W Zhou, H Zhang… - Journal of …, 2023 - Springer
Targeted chemo-phototherapy has received widespread attention in cancer treatment for its
advantages in reducing the side effects of chemotherapeutics and improving therapeutic …

Advancements in Aptamer‐Driven DNA Nanostructures for Precision Drug Delivery

M Safarkhani, S Ahmadi, H Ipakchi, MR Saeb… - Advanced …, 2024 - Wiley Online Library
DNA nanostructures exhibit versatile geometries and possess sophisticated capabilities not
found in other nanomaterials. They serve as customizable nanoplatforms for orchestrating …

Dual-functional DNA nanogels for anticancer drug delivery

H Zhu, J Wu, J Zhao, L Yu, BR Liyarita, X Xu, Y Xiao… - Acta Biomaterialia, 2024 - Elsevier
DNA hydrogels with unique sequence programmability on nucleic acid framework manifest
remarkable attributes, such as high payload capacities, biocompatibility and biosafety. The …

mRNA-responsive two-in-one nanodrug for enhanced anti-tumor chemo-gene therapy

Y Liu, Y Lin, H Xiao, Z Fu, X Zhu, X Chen, C Li… - Journal of Controlled …, 2024 - Elsevier
The combination of chemotherapy and gene therapy holds great promise for the treatment
and eradication of tumors. However, due to significant differences in physicochemical …

A General and Efficient Strategy for Gene Delivery Based on Tea Polyphenols Intercalation and Self‐Polymerization

H Chen, L Guo, J Ding, W Zhou, Y Qi - Advanced Science, 2023 - Wiley Online Library
Gene therapy that employs therapeutic nucleic acids to modulate gene expression has
shown great promise for diseases therapy, and its clinical application relies on the …

Target-Driven Annular DNA Walker Coupled with Electrochemiluminescent Silicon Quantum Dots for APE1 Bioanalysis

YH Li, ML Zhao, P Zhang, X Yang, R Yuan… - Analytical …, 2023 - ACS Publications
Functional DNA walkers with substantial nanostructures have been extensively investigated;
however, their stability still faces challenges when exposed to diverse nuclease in clinical …

Light‐Driven Multi‐Core/Shell Microdroplets as a Targeted Drug Delivery System

S Yuan, B Yao, G Yang, H Lei - Advanced Functional Materials, 2024 - Wiley Online Library
Targeted drug delivery system (DDS) holds exciting prospects in biomedical clinical
research and drug development. However, it faces a significant challenge in achieving …

Photoinduced Reactions of Styrylpyridine Derivatives for the In Situ Formation of Selective Ligands for Apyrimidinic DNA

J Schlosser, N Stötzel, Y Fedorov, H Ihmels - ChemPhotoChem, 2023 - Wiley Online Library
The photocyclization reaction of sterically demanding styrylpyridine derivatives was
investigated and shown to depend on the type of substituent. With this method, a 2, 2 …