Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes
worldwide. The number affected is increasing rapidly with alarming trends in children and …

Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

Abstract Type 2 diabetes (T2D) is a complex chronic disease characterized by considerable
phenotypic heterogeneity. In this study, we applied a reverse graph embedding method to …

Background Research using data-driven cluster analysis has proposed five subgroups of
diabetes with differences in diabetes progression and risk of complications. We aimed to …

Background The association between the triglyceride-glucose (TyG) index and mortality in
cardiovascular disease (CVD) patients with diabetes or pre-diabetes remains unclear. This …

Type 2 diabetes (T2D) is defined by a single metabolite, glucose, but is increasingly
recognized as a highly heterogeneous disease, including individuals with varying clinical …

The current classification of diabetes, based on hyperglycaemia, islet-directed antibodies
and some insufficiently defined clinical features, does not reflect differences in aetiological …

Background Heterogeneity in type 2 diabetes presentation and progression suggests that
precision medicine interventions could improve clinical outcomes. We undertook a …

Type 2 diabetes diagnosed in childhood or early adulthood is termed early-onset type 2
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …

The Precision Medicine in Diabetes Initiative (PMDI) was launched in 2018 by the American
Diabetes Association (ADA) in collaboration with the European Association for the Study of …