[HTML][HTML] Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy
MKK Chan, ELY Chan, ZZ Ji, ASW Chan… - … of Targeted Anti …, 2023 - ncbi.nlm.nih.gov
Transforming growth factor-β (TGF-β) signaling is an important pathway for promoting the
pathogenesis of inflammatory diseases, including cancer. The roles of TGF-β signaling are …
pathogenesis of inflammatory diseases, including cancer. The roles of TGF-β signaling are …
Targeting TGF-β signaling in the multiple myeloma microenvironment: Steering CARs and T cells in the right direction
Multiple myeloma (MM) remains a lethal hematologic cancer characterized by the expansion
of transformed plasma cells within the permissive bone marrow (BM) milieu. The emergence …
of transformed plasma cells within the permissive bone marrow (BM) milieu. The emergence …
Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction–associated steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells
Hepatic fibrosis is the primary determinant of mortality in patients with metabolic dysfunction–
associated steatohepatitis (MASH). Transforming growth factor–β (TGFβ), a master …
associated steatohepatitis (MASH). Transforming growth factor–β (TGFβ), a master …
[HTML][HTML] Role of long non-coding RNAs and TGF-β signaling in the regulation of breast cancer pathogenesis and therapeutic targets
The cytokine known as transforming growth factor (TGF) is essential for cell development,
differentiation, and apoptosis in BC. TGF-β dysregulation can either promote or inhibit tumor …
differentiation, and apoptosis in BC. TGF-β dysregulation can either promote or inhibit tumor …
Coordinated activation of TGF-β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication
A Stavropoulos, G Divolis, M Manioudaki, A Gavriil… - Science …, 2022 - science.org
Ligands of the transforming growth factor–β (TGF-β) superfamily, including TGF-βs, activins,
and bone morphogenetic proteins (BMPs), have been implicated in hepatic development …
and bone morphogenetic proteins (BMPs), have been implicated in hepatic development …
Structural characterization of an inulin neoseries-type fructan from Ophiopogonis Radix and the therapeutic effect on liver fibrosis in vivo
W Liu, L Zhang, X Wei, Y Xu, Q Fang, S Qi, J Chen… - Carbohydrate …, 2024 - Elsevier
Ophiopogonis Radix is a well-known Traditional Chinese Medicine and functional food that
is rich in polysaccharides and has fructan as a characteristic component. In this study, an …
is rich in polysaccharides and has fructan as a characteristic component. In this study, an …
Host immunity and HBV S gene mutation in HBsAg-negative HBV-infected patients
X Liu, S Chen, H Liu, J Lou - Frontiers in Immunology, 2023 - frontiersin.org
Background Clinically, some patients whose HBsAg becomes negative owing to antiviral
therapy or spontaneously still show a low level of HBV DNA persistence in serum. T …
therapy or spontaneously still show a low level of HBV DNA persistence in serum. T …
Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexities
S Ahuja, S Zaheer - Cell Biology International, 2024 - Wiley Online Library
Physiological embryogenesis and adult tissue homeostasis are regulated by transforming
growth factor‐β (TGF‐β), an evolutionarily conserved family of secreted polypeptide factors …
growth factor‐β (TGF‐β), an evolutionarily conserved family of secreted polypeptide factors …
Dynamic changes of cytokine profiles and virological markers during 48 weeks of entecavir treatment for HBeAg-positive chronic hepatitis B
M Li, Y Gao, L Yang, Y Lin, W Deng, T Jiang… - Frontiers in …, 2022 - frontiersin.org
Objective The aims of this study were to investigate the kinetic changes of serum, virological,
and immunological markers during entecavir (ETV) antiviral therapy and to explore whether …
and immunological markers during entecavir (ETV) antiviral therapy and to explore whether …
Potentiation of Sphingolipids and TGF-β in the human corneal stroma reveals intricate signaling pathway crosstalks
Corneal haze brought on by fibrosis due to insult can lead to partial or complete vision loss.
Currently, corneal transplantation is the gold standard for treating severe corneal fibrosis …
Currently, corneal transplantation is the gold standard for treating severe corneal fibrosis …