Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins
We have examined the interactions of the six known rabbit neutrophil defensin antimicrobial
peptides with large unilamellar vesicles (LUV) made from various lipid mixtures based on …
peptides with large unilamellar vesicles (LUV) made from various lipid mixtures based on …
Antimicrobial peptides of leukocytes
Leukocytes use an array of antimicrobial peptides and proteins to help them destroy
invading microorganisms. These endogenous antibiotic molecules are remarkable for their …
invading microorganisms. These endogenous antibiotic molecules are remarkable for their …
Profiling the immune response to periprosthetic joint infection and non-infectious arthroplasty failure
Arthroplasty failure is a major complication of joint replacement surgery. It can be caused by
periprosthetic joint infection (PJI) or non-infectious etiologies, and often requires surgical …
periprosthetic joint infection (PJI) or non-infectious etiologies, and often requires surgical …
The role of antimicrobial peptides in chronic inflammatory skin diseases
M Marcinkiewicz, S Majewski - Advances in Dermatology and …, 2016 - termedia.pl
Antimicrobial peptides (AMPs) are effector molecules of the innate immune system of the
skin. They present an activity against a broad spectrum of Gram-positive and Gram-negative …
skin. They present an activity against a broad spectrum of Gram-positive and Gram-negative …
Synthesis and solution structure of the antimicrobial peptide protegrin‐1
A Aumelas, M Mangoni, C Roumestand… - European Journal of …, 1996 - Wiley Online Library
Protegrins are members of a family of five Cys‐rich, cationic antimicrobial peptides recently
isolated from porcine cells. We have synthesised an 18‐amino‐acid peptide that …
isolated from porcine cells. We have synthesised an 18‐amino‐acid peptide that …
Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes
R Rathinakumar, WC Wimley - Journal of the American Chemical …, 2008 - ACS Publications
Rational design and engineering of membrane-active peptides remains a largely unsatisfied
goal. We have hypothesized that this is due, in part, to the fact that some membrane …
goal. We have hypothesized that this is due, in part, to the fact that some membrane …
A look at arginine in membranes
K Hristova, WC Wimley - The Journal of membrane biology, 2011 - Springer
Here, we review the current knowledge about the energetics of arginine insertion into the
bilayer hydrocarbon core, and we discuss discrepancies between experimental and …
bilayer hydrocarbon core, and we discuss discrepancies between experimental and …
Antibacterial peptides in hemocytes and hematopoietic tissue from freshwater crayfish Pacifastacus leniusculus: characterization and expression pattern
P Jiravanichpaisal, SY Lee, YA Kim, T Andrén… - Developmental & …, 2007 - Elsevier
A 14 amino acid residues proline/arginine-rich antibacterial peptide designated as astacidin
2 was purified and characterized from hemocytes of the freshwater crayfish, Pacifastacus …
2 was purified and characterized from hemocytes of the freshwater crayfish, Pacifastacus …
Thia zip reaction for synthesis of large cyclic peptides: Mechanisms and applications
JP Tam, YA Lu, Q Yu - Journal of the American Chemical Society, 1999 - ACS Publications
This paper describes the mechanism and application of an efficient thia zip cyclization that
involves a series of intramolecular rearrangements in a cysteine-rich peptide for the …
involves a series of intramolecular rearrangements in a cysteine-rich peptide for the …
[HTML][HTML] Cysteine-stabilized αβ defensins: from a common fold to antibacterial activity
R de Oliveira Dias, OL Franco - Peptides, 2015 - Elsevier
Antimicrobial peptides (AMPs) seem to be promising alternatives to common antibiotics,
which are facing increasing bacterial resistance. Among them are the cysteine-stabilized αβ …
which are facing increasing bacterial resistance. Among them are the cysteine-stabilized αβ …