Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …

Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …

Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

Flavonoids are an important class of natural polyphenolic compounds reported to exert
beneficial effects in cardiovascular and metabolic diseases, cancer, autoimmune and …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder of the
central nervous system after Alzheimer's disease. The current understanding of PD focuses …

Ferritin is the main iron storage protein and plays an important role in maintaining iron
homeostasis. In a previous study, we reported that apoferritin exerted a neuroprotective …

Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a classical nuclear
transcription factor that regulates the system's anti-oxidative stress response. The activation …

Due to global population aging and modern lifestyle changes, the incidence of central
nervous system (CNS) disorders, such as neurodegenerative diseases, neuropsychiatric …

Fibroblasts account for more than 95% of dermal cells maintaining dermal structure and
function. However, UVA penetrates the dermis and causes oxidative stress that damages the …

Exosomes are a subset of extracellular vesicles that act as messengers to facilitate
communication between cells. Non-coding RNAs, proteins, lipids, and microRNAs are …