For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …

Exosomes are natural cells-derived vesicles, which are at the forefront toward clinical
success for various diseases, including cerebral ischemia. Exosomes mediate cell-to-cell …

Abstract YTH Domain Containing 1 (YTHDC1) is one of the m6A readers that is essential for
oocyte development and tumor progression. The role of YTHDC1 in neuronal survival and …

Vascular contributions to early cognitive decline are increasingly recognized, prompting
further investigation into the nature of related changes in perivascular spaces (PVS). Using …

There is an ongoing need for accurate prognostic biomarkers in the milieu of acute ischemic
stroke (AIS) receiving reperfusion therapy. Neutrophil–lymphocyte ratio (NLR) has been …

Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …

Intracerebral hemorrhage (ICH) refers to hemorrhage caused by non-traumatic vascular
rupture in the brain parenchyma, which is characterized by acute onset, severe illness, and …

Background and Purpose Systemic immune-inflammation index (SII), a novel inflammation
index derived from counts of circulating platelets, neutrophils and lymphocytes, has been …

Extracellular vesicles (EVs) are promising therapeutic modalities for treating neurological
conditions. EVs facilitate intercellular communication among brain cells under normal and …

Paeoniflorin, a terpenoid glycoside compound extracted from Paeonia lactiflora Pall, shows
preventive and therapeutic effects in various types of nervous system disorders. However, to …