Conclusion Both frailty and sarcopenia are common occurrences in persons older than 55
years with diabetes (Figure 3). They are highly correlated with poor outcomes and are …

Abstract Ketogenic diet (KD), the “High‐fat, low‐carbohydrate, adequate‐protein” diet
strategy, replacing glucose with ketone bodies, is effective against several diseases, from …

Mitochondria play a key role as major regulators of cellular energy homeostasis, but in the
context of mitochondrial dysfunction, mitochondria may generate reactive oxidative species …

Disease-specific biomarkers play a central diagnostic and therapeutic role in muscle
pathology. Serum levels of a variety of muscle-derived enzymes are routinely used for the …

Introduction The global burden of diabetes mellitus is escalating, and more efficient
investigative strategies are needed for a deeper understanding of underlying …

Diabetes mellitus is one of the biggest challenges to human health globally, with an
estimated 95% of the global diabetic population having type 2 diabetes. Classical causes for …

The objective of this study was to characterize the proteome of the corneal endothelial cell
layer and its basement membrane (Descemet membrane) in humans with various severities …

Introduction: Mature skeletal muscles are composed of a complex assembly of slow-
twitching, fast-twitching and hybrid fibres. Since muscle fibres exhibit a high degree of …

In skeletal muscle fibers, the excitation–contraction–relaxation cycle is a highly evolved
process that is mediated by the contractile proteins–myosin and actin–and the regulatory …

Background: Patients with diabetes mellitus (DM) are at risk of experiencing chronic
complications such as retinopathy, nephropathy and myopathy. We aimed to evaluate the …