Oxidative stress and inflammation in osteoporosis: molecular mechanisms involved and the relationship with microRNAs

T Iantomasi, C Romagnoli, G Palmini, S Donati… - International journal of …, 2023 - mdpi.com
Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

Recent advances in natural polyphenol research

I Dini, L Grumetto - Molecules, 2022 - mdpi.com
Polyphenols are secondary metabolites produced by plants, which contribute to the plant's
defense against abiotic stress conditions (eg, UV radiation and precipitation), the aggression …

Emerging roles of circular RNAs in osteoporosis

W Chen, B Zhang, X Chang - Journal of Cellular and Molecular …, 2021 - Wiley Online Library
Osteoporosis is one bone disease characterized with skeletal impairment, bone strength
reduced and fracture risk enhanced. The regulation processes of bone metabolism are …

ncRNAs and polyphenols: new therapeutic strategies for hypertension

E Shirazi-Tehrani, A Chamasemani, N Firouzabadi… - RNA biology, 2022 - Taylor & Francis
Polyphenols have gained significant attention in protecting several chronic diseases, such
as cardiovascular diseases (CVDs). Accumulating evidence indicates that polyphenols have …

Endocrine, Metabolic, and Immune Pathogenesis of Postmenopausal Osteoporosis. Is there a Therapeutic Role in Natural Products?

G Lisco, D Triggiani, VA Giagulli… - … Metabolic & Immune …, 2023 - ingentaconnect.com
Background: Bone health relies on the equilibrium between resorption and new bone
generation. Postmenopausal osteoporosis depends on estrogen deficiency which favorite …

Terpenoid treatment in osteoporosis: This is where we have come in research

D Bellavia, F Caradonna, E Dimarco, V Costa… - Trends in Endocrinology …, 2021 - cell.com
Lower bone resistance to load is due to the imbalance of bone homeostasis, where
excessive bone resorption, compared with bone formation, determines a progressive …

Modulation of Inflammation by Plant-Derived Nutraceuticals in Tendinitis

AL Mueller, A Brockmueller, AB Kunnumakkara… - Nutrients, 2022 - mdpi.com
Tendinitis (tendinopathy) is a pro-inflammatory and painful tendon disease commonly linked
with mechanical overuse and associated injuries, drug abuse, and lifestyle factors (including …

Multiple effects of resveratrol on osteosarcoma cell lines

A De Luca, D Bellavia, L Raimondi, V Carina, V Costa… - Pharmaceuticals, 2022 - mdpi.com
Osteosarcoma (OS) is the most common primary bone sarcoma affecting the life of pediatric
patients. The clinical treatment faces numerous difficulties, including the adverse effects of …

Two important anticancer mechanisms of natural and synthetic chalcones

T Constantinescu, AG Mihis - International Journal of Molecular Sciences, 2022 - mdpi.com
ATP-binding cassette subfamily G and tubulin pharmacological mechanisms decrease the
effectiveness of anticancer drugs by modulating drug absorption and by creating tubulin …

Bioactivity, Molecular Mechanism, and Targeted Delivery of Flavonoids for Bone Loss

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - Nutrients, 2023 - mdpi.com
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …