[HTML][HTML] MicroRNA-21 is a versatile regulator and potential treatment target in central nervous system disorders
X Bai, Z Bian - Frontiers in molecular neuroscience, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of endogenous, non-coding, single-stranded RNAs with a
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
[HTML][HTML] Neuroprotective strategies for traumatic brain injury: improving clinical translation
Traumatic brain injury (TBI) induces secondary biochemical changes that contribute to
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …
[HTML][HTML] Neuroprotection in acute brain injury: an up-to-date review
N Stocchetti, FS Taccone, G Citerio, PE Pepe… - Critical care, 2015 - Springer
Neuroprotective strategies that limit secondary tissue loss and/or improve functional
outcomes have been identified in multiple animal models of ischemic, hemorrhagic …
outcomes have been identified in multiple animal models of ischemic, hemorrhagic …
Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury
At low levels, carbon monoxide (CO) has physiological roles as a second messenger and
neuromodulator 1, 2. Here we assess the effects of CO in a mouse model of traumatic brain …
neuromodulator 1, 2. Here we assess the effects of CO in a mouse model of traumatic brain …
[HTML][HTML] HMGB1-mediated neuroinflammatory responses in brain injuries: potential mechanisms and therapeutic opportunities
Brain injuries are devastating conditions, representing a global cause of mortality and
morbidity, with no effective treatment to date. Increased evidence supports the role of …
morbidity, with no effective treatment to date. Increased evidence supports the role of …
[HTML][HTML] Military-related mild traumatic brain injury: clinical characteristics, advanced neuroimaging, and molecular mechanisms
Mild traumatic brain injury (mTBI) is a significant health burden among military service
members. Although mTBI was once considered relatively benign compared to more severe …
members. Although mTBI was once considered relatively benign compared to more severe …
TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice
X Yao, S Liu, W Ding, P Yue, Q Jiang, M Zhao… - Journal of …, 2017 - Elsevier
Traumatic brain injury (TBI) initiates inflammatory responses that result in an enduring
cascade of secondary neuronal loss and behavioural impairment. Toll-like receptor 4 …
cascade of secondary neuronal loss and behavioural impairment. Toll-like receptor 4 …
[HTML][HTML] Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma
Microglia/macrophages (M) are major contributors to postinjury inflammation, but they may
also promote brain repair in response to specific environmental signals that drive classic …
also promote brain repair in response to specific environmental signals that drive classic …
A porcine model of traumatic brain injury via head rotational acceleration
Unique from other brain disorders, traumatic brain injury (TBI) generally results from a
discrete biomechanical event that induces rapid head movement. The large size and high …
discrete biomechanical event that induces rapid head movement. The large size and high …
Transcranial low-level laser therapy enhances learning, memory, and neuroprogenitor cells after traumatic brain injury in mice
W Xuan, F Vatansever, L Huang… - Journal of biomedical …, 2014 - spiedigitallibrary.org
The use of transcranial low-level laser (light) therapy (tLLLT) to treat stroke and traumatic
brain injury (TBI) is attracting increasing attention. We previously showed that LLLT using an …
brain injury (TBI) is attracting increasing attention. We previously showed that LLLT using an …