Obesity has become a worldwide epidemic, and its prevalence has been projected to grow
by 40% in the next decade. This increasing prevalence has implications for the risk of …

Atherosclerosis is a leading cause of vascular disease worldwide. Its major clinical
manifestations include ischemic heart disease, ischemic stroke, and peripheral arterial …

The American Diabetes Association (ADA)“Standards of Medical Care in Diabetes” includes
the ADA's current clinical practice recommendations and is intended to provide the …

The obesity pandemic continues unabated despite a persistent public health campaign to
decrease energy intake (“eat less”) and increase energy expenditure (“move more”). One …

Cardiovascular disease remains the principal cause of death and disability among patients
with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying …

Background Weight regain after weight loss is a major problem in the treatment of persons
with obesity. Methods In a randomized, head-to-head, placebo-controlled trial, we enrolled …

Abstract Purpose of Review One begins to see improvement in glycemic measures and
triglycerides with small amounts of weight loss, but with greater levels of weight loss there is …

Despite current established therapy, heart failure (HF) remains a leading cause of
hospitalization and mortality worldwide. Novel therapeutic targets are therefore needed to …

Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Obesity and diabetes mellitus have reached epidemic proportions in the past few years.
During 2011 to 2012, more than one-third of the US population was obese. Although recent …