The whole‐body (tachymetabolic) endothermy seen in modern birds and mammals is long
held to have evolved independently in each group, a reasonable assumption when it was …

Alterations in nonshivering thermogenesis are presently discussed as being both potentially
causative of and able to counteract obesity. However, the necessity for mammals to defend …

Obesity has been associated with oxidative stress. Obese patients are at increased risk for
diabetic cognitive dysfunction, indicating a pathological link between obesity, oxidative …

Thermogenesis is one of the most important homeostatic mechanisms that evolved during
vertebrate evolution. Despite its importance for the survival of the organism, the mechanistic …

Circadian oscillation of body temperature is a basic, evolutionarily conserved feature of
mammalian biology. In addition, homeostatic pathways allow organisms to protect their core …

The development of sustained, long-term endothermy was one of the major transitions in the
evolution of vertebrates. Thermogenesis in endotherms does not only occur via shivering or …

Obesity is an escalating threat of pandemic proportions, currently affecting billions of people
worldwide and exerting a devastating socioeconomic influence in industrialized countries …

Thermogenesis is an important homeostatic mechanism essential for survival and normal
physiological functions in mammals. Both brown adipose tissue (BAT)(ie uncoupling protein …

Mitochondrial uncoupling proteins disengage substrate oxidation from ADP phosphorylation
by dissipating the proton electrochemical gradient that is required for ATP synthesis. In …

Avian cold adaptation is hallmarked by innovative strategies of both heat conservation and
thermogenesis. While minimizing heat loss can reduce the thermogenic demands of body …