The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

The reuniens (Re) nucleus is located in the ventral midline thalamus. It has fostered
increasing interest, not only for its participation in a variety of cognitive functions (eg, spatial …

Abstract Rationale and Objectives The prefrontal cortex is critical for execution and inhibition
of reward seeking. Neural manipulation of rodent medial prefrontal cortex (mPFC) …

Cues in the environment signaling the absence of threat, ie safety, can influence both fear
and reward-seeking behaviors. Heightened and maladaptive fear is associated with …

Stressful events can have lasting and impactful effects on behavior, especially by disrupting
normal regulation of fear and reward processing. Accurate discrimination among …

The nucleus accumbens shell (NAcSh) is critically important for reward valuations, yet it
remains unclear how valuation information is integrated in this region to drive behaviour …

The medial prefrontal cortex (mPFC) drives cocaine‐seeking behaviour in rodent models of
cocaine use disorder. Parvalbumin (PV)‐containing GABAergic interneurons powerfully …

The ventromedial prefrontal cortex (vmPFC; rodent infralimbic cortex (IL)), is posited to be an
important locus of fear extinction-facilitating effects of the dopamine (DA) bio-precursor, L …

Early life stress negatively impacts brain development and affects structure and function of
parvalbumin immunopositive (PV+) inhibitory neurons. Main regulators of PV+ interneurons …

Rationale Psychotic disorders such as schizophrenia are often accompanied by high rates
of cigarette smoking, reduced quit success, and high relapse rates, negatively affecting …