Sepsis is a life-threatening disorder disease defined as infection-induced dysregulated
immune responses and multiple organ dysfunction. The imbalance between …

Innate lymphoid cells (ILCs) and macrophages are tissue-resident cells that play important
roles in tissue-immune homeostasis and immune regulation. ILCs are mainly distributed on …

Background: Innate immune memory, also termed “trained immunity”, is thought to protect
against experimental models of infection, including sepsis. Trained immunity via …

Background Sepsis is a heterogeneous disease, therefore the single-gene-based biomarker
is not sufficient to fully understand the disease. Higher-level biomarkers need to be explored …

Sepsis is a syndrome characterized by life-threatening organ dysfunction caused by the
dysregulated host response to an infection. Sepsis, especially septic shock and multiple …

Immunosuppression mediated by CD4+ T cell apoptosis and dysfunction is a key factor in
promoting the progression of sepsis. Endoplasmic reticulum (ER) stress participates in the …

T cells demonstrate high degree of complexity and broad range of functions, which
distinguish them from other immune cells. Throughout their lifetime, T lymphocytes …

Ganoderma lucidum polysaccharides (G. PS) have been recognized for their immune-
modulating properties. In this study, we investigated the impact of G. PS in a sepsis mouse …

Sepsis remains a significant cause of mortality and morbidity worldwide, with limited
effective treatment options. The T-cell immunoglobulin and mucin domain-containing …

Backgrounds Glucose metabolism is associated with the development of cancers, and m6A
RNA methylation regulator-related genes play vital roles in bladder urothelial carcinoma …