The pharmacological case for cannabigerol

R Nachnani, WM Raup-Konsavage, KE Vrana - Journal of Pharmacology …, 2021 - ASPET
Medical cannabis and individual cannabinoids, such as Δ9-tetrahydrocannabinol (Δ9-THC)
and cannabidiol (CBD), are receiving growing attention in both the media and the scientific …

An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives

X Wang, H Zhang, Y Liu, Y Xu, B Yang, H Li… - Bioorganic Chemistry, 2023 - Elsevier
Cannabidiol is a class of non-psychoactive plant cannabinoids derived from cannabis
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …

Cannabidiol goes nuclear: The role of PPARγ

S Khosropoor, MS Alavi, L Etemad, A Roohbakhsh - Phytomedicine, 2023 - Elsevier
Background Cannabidiol (CBD) is one of the main phytocannabinoids found in Cannabis
sativa. In contrast to Δ9-tetrahydrocannabinol, it has a low affinity for cannabinoid receptors …

[HTML][HTML] Resveratrol Attenuates High-Fat Diet Induced Hepatic Lipid Homeostasis Disorder and Decreases m6A RNA Methylation

J Wu, Y Li, J Yu, Z Gan, W Wei, C Wang… - Frontiers in …, 2020 - frontiersin.org
Purpose: N 6-methyladenosine (m6A) mRNA methylation is affected by dietary factors and
associated with lipid metabolism; however, whether the regulatory role of resveratrol in lipid …

[HTML][HTML] Tetrahydrocannabivarin (THCV) protects adipose-derived mesenchymal stem cells (ASC) against endoplasmic reticulum stress development and reduces …

A Kowalczuk, K Marycz, J Kornicka, S Groborz… - International Journal of …, 2023 - mdpi.com
The endoplasmic reticulum (ER) fulfills essential duties in cell physiology, and impairment of
this organelle's functions is associated with a wide number of metabolic diseases. When ER …

[HTML][HTML] Cannabidiol promotes adipogenesis of human and mouse mesenchymal stem cells via PPARγ by inducing lipogenesis but not lipolysis

RC Chang, CS Thangavelu, EM Joloya, A Kuo… - Biochemical …, 2022 - Elsevier
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid found in the Cannabis sativa
plant. Human exposure to CBD can be through recreational marijuana use, commercially …

The therapeutic potential of cannabinoids for integumentary wound management

MA Weigelt, R Sivamani… - Experimental dermatology, 2021 - Wiley Online Library
The increasing legalization of Cannabis for recreational and medicinal purposes in the
United States has spurred renewed interest in the therapeutic potential of cannabinoids …

[HTML][HTML] Chronic cannabidiol administration attenuates skeletal muscle de novo ceramide synthesis pathway and related metabolic effects in a rat model of high-fat …

P Bielawiec, E Harasim-Symbor… - Biomolecules, 2020 - mdpi.com
Numerous studies showed that sustained obesity results in accumulation of bioactive lipid
derivatives in several tissues, including skeletal muscle, which further contributes to the …

[HTML][HTML] Cannabidiol (CBD) protects adipose-derived mesenchymal stem cells (ASCs) against endoplasmic reticulum stress development and its complications

A Kowalczuk, K Marycz, K Kornicka-Garbowska… - International Journal of …, 2022 - mdpi.com
Background: Recent studies suggested that individuals with metabolic disorders have
altered function of adipocytes and adipose stem cell subpopulations, which impairs tissue …

[HTML][HTML] Identification and Characterization of Cannabimovone, a Cannabinoid from Cannabis sativa, as a Novel PPARγ Agonist via a Combined Computational and …

FA Iannotti, F De Maio, E Panza, G Appendino… - Molecules, 2020 - mdpi.com
Phytocannabinoids (pCBs) are a large family of meroterpenoids isolated from the plant
Cannabis sativa. Δ9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the best …