Extracellular vesicles in metabolic syndrome

MC Martínez, R Andriantsitohaina - Circulation research, 2017 - Am Heart Assoc
Metabolic syndrome defines a cluster of interrelated risk factors for cardiovascular disease
and diabetes mellitus. These factors include metabolic abnormalities, such as …

[HTML][HTML] Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild …

K Warmink, JL Rios, S Varderidou-Minasian… - Stem cell research & …, 2023 - Springer
Background Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular
vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA) …

The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche

L Blavier, R Nakata, P Neviani… - Journal of …, 2023 - Wiley Online Library
The capture of tumour‐derived extracellular vesicles (TEVs) by cells in the tumour
microenvironment (TME) contributes to metastasis and notably to the formation of the pre …

Towards Therapeutic Delivery of Extracellular Vesicles: Strategies for In Vivo Tracking and Biodistribution Analysis

G Di Rocco, S Baldari, G Toietta - Stem cells international, 2016 - Wiley Online Library
Extracellular vesicles (EVs), such as microvesicles and exosomes, are membranous
structures containing bioactive material released by several cells types, including …

Human periodontal ligament stem cell‐derived exosomes promote bone regeneration by altering MicroRNA profiles

T Liu, W Hu, X Zou, J Xu, S He, L Chang… - Stem Cells …, 2020 - Wiley Online Library
The role and underlying mechanism of exosomes derived from human periodontal ligament
stem cells (PDLSC) in osteogenesis are unclear. In the present study, we identified the …

Cellular mechanisms of liver regeneration and cell‐based therapies of liver diseases

IV Kholodenko, KN Yarygin - BioMed research international, 2017 - Wiley Online Library
The emerging field of regenerative medicine offers innovative methods of cell therapy and
tissue/organ engineering as a novel approach to liver disease treatment. The ultimate …

[HTML][HTML] A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice

P Gangadaran, XJ Li, HW Lee, JM Oh, S Kalimuthu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
In vivo biodistribution and fate of extracellular vesicles (EVs) are still largely unknown and
require reliable in vivo tracking techniques. In this study, in vivo bioluminescence imaging …

Diagnostic and therapeutic potential of extracellular vesicles

SP Kodam, M Ullah - Technology in Cancer Research & …, 2021 - journals.sagepub.com
Extracellular vesicles (EVs) are naturally phospholipid enclosed nanovesicles released by
many cells in the body. They are stable in circulation, have low immunogenicity, and act as …

[HTML][HTML] Insights into the effects of mesenchymal stem cell-derived secretome in Parkinson's disease

M d'Angelo, A Cimini, V Castelli - International Journal of Molecular …, 2020 - mdpi.com
Mesenchymal stem cell (MSC)-derived secretome demonstrated therapeutic effects like
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: a promising therapeutic ace card to address autoimmune diseases

H Baharlooi, M Azimi, Z Salehi… - International journal of …, 2020 - synapse.koreamed.org
With the development of novel treatments for autoimmune disorders, it has become a
popular research focus which mesenchymal stem cells (MSCs) have the capacity to …