Comparative analysis of lymphocyte activation marker expression and cytokine secretion profile in stimulated human peripheral blood mononuclear cell cultures: an in …

M Reddy, E Eirikis, C Davis, HM Davis… - Journal of immunological …, 2004 - Elsevier
Activation of lymphocytes is a complex, yet finely regulated cascade of events that results in
the expression of cytokine receptors, production and secretion of cytokines and expression …

The biology of transferrin

G De Jong, JP Van Dijk, HG Van Eijk - Clinica chimica acta, 1990 - Elsevier
The chemistry and molecular biology of transferrin is discussed. The discussion covers the
genetic control of transferrin synthesis, its intracellular synthesis, intra-and extracellular …

Contingent genetic regulatory events in T lymphocyte activation

GR Crabtree - Science, 1989 - science.org
Interaction of antigen in the proper histocompatibility context with the T lymphocyte antigen
receptor leads to an orderly series of events resulting in morphologic change, proliferation …

The iron metabolism of neoplastic cells: alterations that facilitate proliferation?

JC Kwok, DR Richardson - Critical reviews in oncology/hematology, 2002 - Elsevier
For many years it has been known that neoplastic cells express high levels of the transferrin
receptor 1 (TfR1) and internalize iron (Fe) from transferrin (Tf) at a tremendous rate …

Lupus nephritis: correlation of interstitial cells with glomerular function

E Alexopoulos, D Seron, RB Hartley, JS Cameron - Kidney international, 1990 - Elsevier
Lupus nephritis: Correlation of interstitial cells with glomerular function. Mononuclear
inflammatory cells were studied using monoclonal antibodies in the interstitium and …

Iron metabolism in the lower respiratory tract

F Mateos, JH Brock, JL Pérez-Arellano - Thorax, 1998 - thorax.bmj.com
Background Iron is principally required for haemoglobin synthesis, and its uptake, utilisation
and storage are carefully regulated to ensure an adequate supply without excessive …

[PDF][PDF] Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: achievements and prospects

M Cazzola, G Bergamaschi, L Dezza, P Arosio - 1990 - researchgate.net
Iron-containing proteins of the respiratory chain are involved in electron transport to provide
the energy for cellular functional activities.'Iron is also required for cell growth and …

Regulation of interleukin 2-driven T-lymphocyte proliferation by prolactin.

CV Clevenger, DH Russell… - Proceedings of the …, 1990 - National Acad Sciences
The requirement for prolactin in interleukin 2-driven T-cell proliferation was evaluated.
Addition of an anti-prolactin antiserum resulted in the specific inhibition of T-cell proliferation …

Iron homeostasis in breast cancer

O Marques, BM da Silva, G Porto, C Lopes - Cancer letters, 2014 - Elsevier
Iron is an essential element and a critical component of molecules involved in energy
production, cell cycle and intermediate metabolism. However, the same characteristic …

Transferrin and the transferrin receptor: of magic bullets and other concerns

MF Macedo, M Sousa - Inflammation & Allergy-Drug Targets …, 2008 - ingentaconnect.com
Transferrin (Trf) is a highly conserved serum glycoprotein mostly known for its iron transport
capacity. As iron is an indispensable nutrient for cell division, Trf and its receptor have long …