Imaging the limbic system in Parkinson's disease—a review of limbic pathology and clinical symptoms

M Banwinkler, H Theis, S Prange, T van Eimeren - Brain sciences, 2022 - mdpi.com
The limbic system describes a complex of brain structures central for memory, learning, as
well as goal directed and emotional behavior. In addition to pathological studies, recent …

Functional connectivity signatures of Parkinson's disease

A Tessitore, M Cirillo… - Journal of Parkinson's …, 2019 - content.iospress.com
Resting-state functional magnetic resonance imaging (RS-fMRI) studies have been
extensively applied to analyze the pathophysiology of neurodegenerative disorders such as …

The cerebellum directly modulates the substantia nigra dopaminergic activity

S Washburn, M Oñate, J Yoshida, J Vera… - Nature …, 2024 - nature.com
Evidence of direct reciprocal connections between the cerebellum and basal ganglia has
challenged the long-held notion that these structures function independently. While …

Functional brain dysconnectivity in Parkinson's disease: a 5‐year longitudinal study

S Yassine, U Gschwandtner, M Auffret… - Movement …, 2022 - Wiley Online Library
Background Tracking longitudinal functional brain dysconnectivity in Parkinson's disease
(PD) is a key element to decoding the underlying physiopathology and understanding PD …

Machine learning for detecting parkinson's disease by resting-state functional magnetic resonance imaging: A multicenter radiomics analysis

D Shi, H Zhang, G Wang, S Wang, X Yao… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease (PD) is one of the most common progressive degenerative diseases,
and its diagnosis is challenging on clinical grounds. Clinically, effective and quantifiable …

Longitudinal brain connectivity changes and clinical evolution in Parkinson's disease

M Filippi, S Basaia, E Sarasso, T Stojkovic… - Molecular …, 2021 - nature.com
Longitudinal connectivity studies might guide our understanding of the underlying
neurodegenerative processes. We report the results of a longitudinal study in patients at …

Resting‐state functional MRI in Parkinsonian syndromes

M Filippi, E Sarasso, F Agosta - Movement disorders clinical …, 2019 - Wiley Online Library
ABSTRACT Background Functional MRI (fMRI) has been widely used to study abnormal
patterns of functional connectivity at rest in patients with movement disorders such as …

Decoupling of interacting neuronal populations by time-shifted stimulation through spike-timing-dependent plasticity

M Madadi Asl, A Valizadeh, PA Tass - PLOS Computational …, 2023 - journals.plos.org
The synaptic organization of the brain is constantly modified by activity-dependent synaptic
plasticity. In several neurological disorders, abnormal neuronal activity and pathological …

Functional Connectomics and disease progression in drug‐naive Parkinson's disease patients

R De Micco, F Agosta, S Basaia, M Siciliano… - Movement …, 2021 - Wiley Online Library
Background Functional brain connectivity alterations may be detectable even before the
occurrence of brain atrophy, indicating their potential as early markers of pathological …

Dynamics of top‐down control and motor networks in Parkinson's disease

L Chen, P Bedard, M Hallett… - Movement Disorders, 2021 - Wiley Online Library
Abstract Background Motor symptoms in Parkinson's disease (PD) patients might be related
to high‐level task‐control deficits. We aimed at investigating the dynamics between …