Cadmium is a nonessential metal that has heavily polluted the environment due to human
activities. It can be absorbed into the human body via the gastrointestinal tract, respiratory …

Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …

Free radicals contain one or more unpaired electrons in their valence shell, thus making
them unstable, short-lived, and highly reactive species. Excessive generation of these free …

Rationale: Sepsis is a severe clinical syndrome featured through organ dysfunction due to
infection, while the accompanying acute kidney injury (AKI) is linked to significant incidence …

Acute kidney injury (AKI) is mainly caused by renal ischaemia reperfusion injury (IRI). Lots of
evidence suggests that ferroptosis and oxidative stress play the vital role in renal IRI …

Transforming growth factor-β (TGF-β) induces pro-inflammatory cytokines expression
including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) and these cytokines …

Fibrosis describes a dysregulated tissue remodelling response to persistent cellular injury
and is the final pathological consequence of many chronic diseases that affect the liver …

This study aims to investigate whether stabilization of glucagon-like peptide-1 (GLP-1) level
reduces angiotensin II (Ang II)-induced cardiac fibrosis and-elevated blood pressure …

Increased left ventricular fibrosis has been reported in patients hospitalized with coronavirus
disease 2019 (COVID-19). It is unclear whether this fibrosis is a consequence of severe …

The ureohydrolase, type-II arginase (Arg-II), is a mitochondrial enzyme metabolizing L-
arginine into urea and L-ornithine and is highly expressed in renal proximal tubular cells …