Shikonin attenuates kidney tubular epithelial cells apoptosis, oxidative stress, and inflammatory response through nicotinamide adenine dinucleotide phosphate …
Y Peng, Y Li, H Li, J Yu - Drug Development Research, 2022 - Wiley Online Library
Natural compounds were used in the treatment of acute kidney injury (AKI) caused by
sepsis. This study investigated the function of shikonin from the roots of Arnebia purpurea in …
sepsis. This study investigated the function of shikonin from the roots of Arnebia purpurea in …
[HTML][HTML] Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in …
J He, YL Jiang, Y Wang, XJ Tian… - Chinese medical …, 2020 - journals.lww.com
Background The use of microRNAs in the therapy of kidney disease is hampered by the
difficulties in their effective delivery. Micro-vesicles (MVs) are known as natural carriers of …
difficulties in their effective delivery. Micro-vesicles (MVs) are known as natural carriers of …
[HTML][HTML] The effect of repeated passaging on the susceptibility of human proximal tubular HK-2 cells to toxic compounds
J Handl, J Čapek, P Majtnerová, J Báčová… - Physiological …, 2020 - ncbi.nlm.nih.gov
The human proximal tubular HK-2 cell line is an immortalized cell line commonly used for
studying proximal tubular toxicity. Even as their use is presently increasing, there …
studying proximal tubular toxicity. Even as their use is presently increasing, there …
Inhibition of both NOX and TNF-α exerts substantial renoprotective effects in renal ischemia reperfusion injury rat model
AA Bayoumi, EA Ahmad, IAAEH Ibrahim… - European Journal of …, 2024 - Elsevier
Background and aims Acute kidney injury (AKI) due to renal ischemia-reperfusion injury
(RIRI) is associated with high morbidity and mortality, with no renoprotective drug available …
(RIRI) is associated with high morbidity and mortality, with no renoprotective drug available …
低氧诱导因子1α 与低氧相关疾病信号通路的关系
顾霞， 赵敏， 王平义， 李一梅， 李文华 - 中国组织工程研究, 2021 - cjter.com
低氧诱导因子1α 与低氧相关疾病信号通路的关系 Page 1 1284 |中国组织工程研究|第25卷|第8期
|2021年3月 低氧诱导因子1α 与低氧相关疾病信号通路的关系 顾霞,赵敏,王平义,李一梅,李文华 …
|2021年3月 低氧诱导因子1α 与低氧相关疾病信号通路的关系 顾霞,赵敏,王平义,李一梅,李文华 …
[HTML][HTML] NADPH-oxidase derived hydrogen peroxide and Irs2b facilitate re-oxygenation-induced catch-up growth in zebrafish embryo
A Zasu, F Hishima, M Thauvin, Y Yoneyama… - Frontiers in …, 2022 - frontiersin.org
Oxygen deprivation induces multiple changes at the cellular and organismal levels, and its
re-supply also brings another special physiological status. We have investigated the effects …
re-supply also brings another special physiological status. We have investigated the effects …
[HTML][HTML] Specific NOX4 Inhibition Preserves Mitochondrial Function and Dampens Kidney Dysfunction Following Ischemia–Reperfusion-Induced Kidney Injury
TA Schiffer, LRRA Carvalho, D Guimaraes, A Boeder… - Antioxidants, 2024 - mdpi.com
Highlights What are the main findings? NADPH oxidases (NOXs) are induced following
ischemia-reperfusion (IR), which aggravates acute kidney injury NOX4 inhibition improves …
ischemia-reperfusion (IR), which aggravates acute kidney injury NOX4 inhibition improves …
Oxygen and embryonic growth: the role of insulin-like growth factor signaling
H Kamei - General and Comparative Endocrinology, 2020 - Elsevier
Oxygen is indispensable for the efficient release of chemical energy from nutrient molecules
in cells. Therefore, the local oxygen tension is one of the most critical factors affecting …
in cells. Therefore, the local oxygen tension is one of the most critical factors affecting …
[PDF][PDF] 急性肾损伤动物模型构建方法与研究现状
张佳莉， 张岩 - 中国实验动物学报, 2022 - zgbjyx.cnjournals.com
Acute kidney injury (AKI) is a common disease in clinical practice, and its incidence is
increasing yearly along with a high mortality rate. Therefore, establishment of reliable, stable …
increasing yearly along with a high mortality rate. Therefore, establishment of reliable, stable …
Downregulation of NOX4 improves airway remodeling and inflammation by the TGF-β1-Smad2/3 pathway in asthma
A Xuan, M Yang, Q Xia, Q Sun - Cellular and Molecular Biology, 2023 - cellmolbiol.org
Asthma is a respiratory inflammatory disease, and nicotinamide adenine dinucleotide
phosphate oxidase 4 (NOX4) is involved in the progression of respiratory diseases …
phosphate oxidase 4 (NOX4) is involved in the progression of respiratory diseases …