A considerable amount of continuous proliferation and differentiation is required to produce
daily a billion new neutrophils in an adult human. Of the few cytokines and factors known to …

Serine/arginine-rich splicing factor 2 (SRSF2) is a splicing factor that is widely expressed in
a variety of mammalian cell types. Increasing evidence has confirmed that SRSF2 plays vital …

Serine/arginine-rich splicing factors (SRSFs) refer to twelve RNA-binding proteins which
regulate splice site recognition and spliceosome assembly during precursor messenger …

Background Machine learning is one kind of machine intelligence technique that learns from
data and detects inherent patterns from large, complex datasets. Due to this capability …

Background RNA splicing plays significant roles in fundamental biological activities.
However, our knowledge about the roles of alternative splicing and underlying mechanisms …

Alternatively spliced colony stimulating factor 3 receptor (CSF3R) isoforms Class III and
Class IV are observed in myelodysplastic syndromes (MDS), but their roles in disease …

Background Genome-wide association studies have found many genetic risk variants
associated with Alzheimer's disease (AD). However, how these risk variants affect deeper …

Cytokine and cytokine receptors are important regulators of hematopoiesis. Hematopoietic
stem cells (HSCs) and progenitors differentiate into the myeloid or lymphoid lineage in …

RNA splicing plays significant roles in fundamental biological activities. However, our
knowledge about the roles of alternative splicing and underlying mechanisms during …

Inflammatory bowel diseases (IBDs), which primarily include Crohn's disease (CD) and
ulcerative colitis (UC), are chronic recurrent diseases of the gastrointestinal tract with …