Known risk variants explain only a small proportion of breast cancer heritability, particularly
in Asian women. To search for additional genetic susceptibility loci for breast cancer, here …

Abstract Background The potential of Mendelian randomization studies is rapidly expanding
due to:(i) the growing power of genome-wide association study (GWAS) meta-analyses to …

Genome-wide association studies (GWAS) have identified numerous common prostate
cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the …

Abstract Prostate cancer incidence is 1.6-fold higher in African Americans than in other
populations. The risk factors that drive this disparity are unknown and potentially consist of …

This article is a review of approaches to treatment of low and high-grade prostate cancer
including a discussion of active treatment vs. active surveillance for patients with low-grade …

African-American men are more likely than any other racial group to die from prostate
cancer. The contribution of acquired genomic variation to this racial disparity is largely …

Background Recent genome-wide association studies (GWAS) have identified more than
100 loci associated with increased risk of prostate cancer, most of which are in non-coding …

Prostate cancer (CaP) is the most commonly diagnosed non-cutaneous cancer and the
second leading cause of male cancer deaths in the United States. Among African American …

Prostate cancer (PCa) brings huge public health burden in men. A growing number of
conventional observational studies report associations of multiple circulating proteins with …

A major consequence of the world industrialized lifestyle is the increasing period of
unnatural light in environments during the day and artificial lighting at night. This major …