Evolving roles of natural terpenoids from traditional Chinese medicine in the treatment of osteoporosis
Y Zhuo, M Li, Q Jiang, H Ke, Q Liang… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis (OP) is a systemic metabolic skeletal disease which can lead to reduction in
bone mass and increased risk of bone fracture due to the microstructural degradation …
bone mass and increased risk of bone fracture due to the microstructural degradation …
Pharmacological and mechanistic aspects of quercetin in osteoporosis
TT Deng, WY Ding, XX Lu, QH Zhang, JX Du… - Frontiers in …, 2024 - frontiersin.org
Osteoporosis (OP) is a bone disease associated with increasing age. Currently, the most
common medications used to treat OP are anabolic agents, anti-resorptive agents, and …
common medications used to treat OP are anabolic agents, anti-resorptive agents, and …
Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis
T Wang, L Fan, S Feng, X Ding, X An, J Chen… - Scientific reports, 2022 - nature.com
Eucommia ulmoides Oliver is one of the commonly used traditional Chinese medicines for
the treatment of osteoporosis, and iridoid glycosides are considered to be its active …
the treatment of osteoporosis, and iridoid glycosides are considered to be its active …
Integrative analysis reveals the diverse effects of 3D stiffness upon stem cell fate
M Yue, Y Liu, P Zhang, Z Li, Y Zhou - International Journal of Molecular …, 2023 - mdpi.com
The origin of life and native tissue development are dependent on the heterogeneity of
pluripotent stem cells. Bone marrow mesenchymal stem cells (BMMSCs) are located in a …
pluripotent stem cells. Bone marrow mesenchymal stem cells (BMMSCs) are located in a …
Isoliquiritin treatment of osteoporosis by promoting osteogenic differentiation and autophagy of bone marrow mesenchymal stem cells
Z Su, D Chen, J Huang, Z Liang, W Ren… - Phytotherapy …, 2024 - Wiley Online Library
Osteoporosis is a chronic progressive bone disease characterized by the decreased
osteogenic ability of osteoblasts coupled with increased osteoclast activity. Natural products …
osteogenic ability of osteoblasts coupled with increased osteoclast activity. Natural products …
Hypoxia preconditioning of adipose stem cell-derived exosomes loaded in gelatin methacryloyl (GelMA) promote type H angiogenesis and osteoporotic fracture repair
X Li, S Fang, S Wang, Y Xie, Y Xia, P Wang… - Journal of …, 2024 - Springer
The challenges posed by delayed atrophic healing and nonunion stand as formidable
obstacles in osteoporotic fracture treatment. The processes of type H angiogenesis and …
obstacles in osteoporotic fracture treatment. The processes of type H angiogenesis and …
Gut metabolite urolithin A inhibits osteoclastogenesis and senile osteoporosis by enhancing the autophagy capacity of bone marrow macrophages
H Tao, Y Tao, C Yang, W Li, W Zhang, X Li… - Frontiers in …, 2022 - frontiersin.org
Senile osteoporosis (SOP) is a systemic bone disease that is significantly associated with
age and eventually leads to deteriorated bone strength and increased fracture risk. Urolithin …
age and eventually leads to deteriorated bone strength and increased fracture risk. Urolithin …
The effects of epigenetic modifications on bone remodeling in age-related osteoporosis
Purpose: As the population ages, there is an increased risk of fracture and morbidity
diseases associated with aging, such as age-related osteoporosis and other bone diseases …
diseases associated with aging, such as age-related osteoporosis and other bone diseases …
Morroniside ameliorates glucocorticoid-induced osteoporosis and promotes osteoblastogenesis by interacting with sodium-glucose cotransporter 2
HZ Yang, R Dong, Y Jia, Y Li, G Luo, T Li… - Pharmaceutical …, 2023 - Taylor & Francis
Context Morroniside (MOR) possesses antiosteoporosis (OP) effects, but its molecular target
and relevant mechanisms remain unknown. Objective We investigated the effects of MOR on …
and relevant mechanisms remain unknown. Objective We investigated the effects of MOR on …
[HTML][HTML] Epoxymicheliolide inhibits osteoclastogenesis and resists OVX-induced osteoporosis by suppressing ERK1/2 and NFATc1 signaling
F Long, R Chen, Y Su, J Liang, Y Xian, F Yang… - International …, 2022 - Elsevier
The hyperactivity of osteoclasts caused by postmenopausal estrogen deficiency plays an
imperative role in the progression of osteoporosis. Although osteoporosis-related drugs …
imperative role in the progression of osteoporosis. Although osteoporosis-related drugs …