In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …

Breast cancer, as a highly heterogeneous malignant tumor, is one of the primary causes of
death among females worldwide. The etiology of breast cancer involves aberrant epigenetic …

Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals.
However, HDL from patients with coronary artery disease undergoes various modifications …

Tumor is a local tissue hyperplasia resulted from cancerous transformation of normal cells
under the action of various physical, chemical and biological factors. The exploration of …

Abstract TP53 mutation (TP53 mut) occurs in 10–20% of diffuse large B-cell lymphoma
(DLBCL) cases and serves as an unfavorable biomarker of DLBCL progression. It confers …

Up till the present moment, breast cancer is still the leading cause of cancer-related death in
women worldwide. Although the treatment methods and protocols for breast cancer are …

Background Downregulation of certain tumor-suppressor genes (TSGs) by aberrant
methylation of CpG islands in the promoter region contributes a great deal to the …

Esophageal cancer is a widespread cancer of the digestive system that has two main
subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma …

Although cancer has long been considered a genetic disease, increasing evidence shows
that epigenetic aberrations play a crucial role in affecting tumor biology and therapeutic …

Mutations or abnormal expression of oncogenes and tumor suppressor genes are known to
cause cancer. Recent studies have shown that epigenetic modifications are key drivers of …