CRISPR/Cas Systems‐Inspired Nano/Biosensors for Detecting Infectious Viruses and Pathogenic Bacteria
Infectious pathogens cause severe human illnesses and great deaths per year worldwide.
Rapid, sensitive, and accurate detection of pathogens is of great importance for preventing …
Rapid, sensitive, and accurate detection of pathogens is of great importance for preventing …
CRISPR/Cas-powered amplification-free detection of nucleic acids: current state of the art, challenges, and futuristic perspectives
Y Li, Y Liu, X Tang, J Qiao, J Kou, S Man, L Zhu… - ACS …, 2023 - ACS Publications
CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …
repositioned in nucleic acid detection. A preamplification step is usually required to improve …
[HTML][HTML] CRISPR-Cas13a system: A novel tool for molecular diagnostics
L Zhao, M Qiu, X Li, J Yang, J Li - Frontiers in Microbiology, 2022 - frontiersin.org
The clustered regularly interspaced short palindromic repeats (CRISPR) system is a natural
adaptive immune system of prokaryotes. The CRISPR-Cas system is currently divided into …
adaptive immune system of prokaryotes. The CRISPR-Cas system is currently divided into …
Cas12a-assisted RTF-EXPAR for accurate, rapid and simple detection of SARS-CoV-2 RNA
XM Hang, HY Wang, PF Liu, KR Zhao… - Biosensors and …, 2022 - Elsevier
Developing highly accurate and simple approaches to rapidly identify and isolate SARS-
CoV-2 infected patients is important for the control of the COVID-19 pandemic. We, herein …
CoV-2 infected patients is important for the control of the COVID-19 pandemic. We, herein …
CRISPR/Cas13a-triggered Cas12a biosensing method for ultrasensitive and specific miRNA detection
D Zhao, J Tang, Q Tan, X Xie, X Zhao, D Xing - Talanta, 2023 - Elsevier
Constructing an ultrasensitive CRISPR/Cas-based biosensing strategy is highly significant
for the detection of trace targets. Here we presented a dual-amplified biosensing method …
for the detection of trace targets. Here we presented a dual-amplified biosensing method …
The rate-limiting procedure of 3D DNA walkers and their applications in tandem technology
H Ma, L Chen, J Lv, X Yan, Y Li, G Xu - Chemical Communications, 2023 - pubs.rsc.org
DNA walkers, an artificial dynamic DNA nanomachine, can mimic actin to move rapidly
along a predefined nucleic acid track. They can generally be classified one-(1D), two-(2D) …
along a predefined nucleic acid track. They can generally be classified one-(1D), two-(2D) …
[HTML][HTML] RNA-dependent RNA targeting by CRISPR-cas systems: characterizations and applications
N Gunitseva, M Evteeva, A Borisova… - International Journal of …, 2023 - mdpi.com
Genome editing technologies that are currently available and described have a fundamental
impact on the development of molecular biology and medicine, industrial and agricultural …
impact on the development of molecular biology and medicine, industrial and agricultural …
CRISPR-based nucleic acid diagnostics for pathogens
H Yang, Y Zhang, X Teng, H Hou, R Deng… - TrAC Trends in Analytical …, 2023 - Elsevier
Pathogenic infection remains the primary threat to human health, such as the global COVID-
19 pandemic. It is important to develop rapid, sensitive and multiplexed tools for detecting …
19 pandemic. It is important to develop rapid, sensitive and multiplexed tools for detecting …
[HTML][HTML] CRISPR-based biosensor for the detection of Marburg and Ebola virus
Marburg Virus is one of the most neglected diseases that dated back to 1967. Prior to the
21st century, the outbreak of the virus was recorded trice, In 1967, 1998 and 2004. Accurate …
21st century, the outbreak of the virus was recorded trice, In 1967, 1998 and 2004. Accurate …
Ultra-sensitive and specificity quantitative detection of miRNA using a combined CRISPR/Cas13a and DNA-PAINT
Z Xu, L Guan, J Peng, S Huang, T Liu, T Xiong… - Sensors and Actuators B …, 2023 - Elsevier
MicroRNAs (miRNAs) are considered to be important biomarkers for the diagnosis of
numerous diseases and basic biomedical research. Therefore, a novel rapid diagnostic …
numerous diseases and basic biomedical research. Therefore, a novel rapid diagnostic …