Chemistry can make strict and fuzzy controls for bio-systems: DNA nanoarchitectonics and cell-macromolecular nanoarchitectonics

M Komiyama, K Yoshimoto, M Sisido… - Bulletin of the Chemical …, 2017 - academic.oup.com
In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …

[HTML][HTML] RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications

H Li, T Lee, T Dziubla, F Pi, S Guo, J Xu, C Li, F Haque… - Nano today, 2015 - Elsevier
The value of polymers is manifested in their vital use as building blocks in material and life
sciences. Ribonucleic acid (RNA) is a polynucleic acid, but its polymeric nature in materials …

Generation of aptamers with an expanded chemical repertoire

S Diafa, M Hollenstein - Molecules, 2015 - mdpi.com
The enzymatic co-polymerization of modified nucleoside triphosphates (dN* TPs and N*
TPs) is a versatile method for the expansion and exploration of expanded chemical space in …

Beyond ribose and phosphate: selected nucleic acid modifications for structure–function investigations and therapeutic applications

C Liczner, K Duke, G Juneau, M Egli… - Beilstein Journal of …, 2021 - beilstein-journals.org
Over the past 25 years, the acceleration of achievements in the development of
oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the …

Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential

M Strenkowska, R Grzela, M Majewski… - Nucleic acids …, 2016 - academic.oup.com
Along with a growing interest in mRNA-based gene therapies, efforts are increasingly
focused on reaching the full translational potential of mRNA, as a major obstacle for in vivo …

DNA aptamer–target binding motif revealed using a fluorescent guanine probe: implications for food toxin detection

KL Fadock, RA Manderville - ACS omega, 2017 - ACS Publications
DNA aptamers are single-stranded oligonucleotides that are generated by an in vitro
selection method to bind targets with high affinity and specificity. Understanding molecular …

Synthesis of Responsive Two‐Dimensional Polymers via Self‐Assembled DNA Networks

H Yu, DTL Alexander, U Aschauer… - Angewandte Chemie …, 2017 - Wiley Online Library
Despite a growing interest in two‐dimensional polymers, their rational synthesis remains a
challenge. The solution‐phase synthesis of a two‐dimensional polymer is reported. A DNA …

Supramolecular assembly of DNA-phenanthrene conjugates into vesicles with light-harvesting properties

CD Bösch, J Jevric, N Bürki, M Probst… - Bioconjugate …, 2018 - ACS Publications
Vesicle-shaped supramolecular polymers are formed by self-assembly of a DNA duplex
containing phenanthrene overhangs at both ends. In the presence of spermine, the …

A simple molecular rotor for defining nucleoside environment within a DNA aptamer–protein complex

TZ Cservenyi, AJ Van Riesen, FD Berger… - ACS chemical …, 2016 - ACS Publications
The simple 5-furyl-2′-deoxyuridine (FurdU) nucleobase exhibits dual probing
characteristics displaying emissive sensitivity to changes in microenvironment polarity and …

Formation of Two Homo‐chromophoric H‐Aggregates in DNA‐Assembled Alternating Dye Stacks

CB Winiger, SM Langenegger, G Calzaferri… - Angewandte …, 2015 - Wiley Online Library
The understanding and description of collectively excited multichromophores is of crucial
importance for many areas of basic and applied research. DNA has been used for the …