Chemistry can make strict and fuzzy controls for bio-systems: DNA nanoarchitectonics and cell-macromolecular nanoarchitectonics
M Komiyama, K Yoshimoto, M Sisido… - Bulletin of the Chemical …, 2017 - academic.oup.com
In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …
[HTML][HTML] RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications
The value of polymers is manifested in their vital use as building blocks in material and life
sciences. Ribonucleic acid (RNA) is a polynucleic acid, but its polymeric nature in materials …
sciences. Ribonucleic acid (RNA) is a polynucleic acid, but its polymeric nature in materials …
Generation of aptamers with an expanded chemical repertoire
S Diafa, M Hollenstein - Molecules, 2015 - mdpi.com
The enzymatic co-polymerization of modified nucleoside triphosphates (dN* TPs and N*
TPs) is a versatile method for the expansion and exploration of expanded chemical space in …
TPs) is a versatile method for the expansion and exploration of expanded chemical space in …
Beyond ribose and phosphate: selected nucleic acid modifications for structure–function investigations and therapeutic applications
C Liczner, K Duke, G Juneau, M Egli… - Beilstein Journal of …, 2021 - beilstein-journals.org
Over the past 25 years, the acceleration of achievements in the development of
oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the …
oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the …
Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential
M Strenkowska, R Grzela, M Majewski… - Nucleic acids …, 2016 - academic.oup.com
Along with a growing interest in mRNA-based gene therapies, efforts are increasingly
focused on reaching the full translational potential of mRNA, as a major obstacle for in vivo …
focused on reaching the full translational potential of mRNA, as a major obstacle for in vivo …
DNA aptamer–target binding motif revealed using a fluorescent guanine probe: implications for food toxin detection
KL Fadock, RA Manderville - ACS omega, 2017 - ACS Publications
DNA aptamers are single-stranded oligonucleotides that are generated by an in vitro
selection method to bind targets with high affinity and specificity. Understanding molecular …
selection method to bind targets with high affinity and specificity. Understanding molecular …
Synthesis of Responsive Two‐Dimensional Polymers via Self‐Assembled DNA Networks
H Yu, DTL Alexander, U Aschauer… - Angewandte Chemie …, 2017 - Wiley Online Library
Despite a growing interest in two‐dimensional polymers, their rational synthesis remains a
challenge. The solution‐phase synthesis of a two‐dimensional polymer is reported. A DNA …
challenge. The solution‐phase synthesis of a two‐dimensional polymer is reported. A DNA …
Supramolecular assembly of DNA-phenanthrene conjugates into vesicles with light-harvesting properties
CD Bösch, J Jevric, N Bürki, M Probst… - Bioconjugate …, 2018 - ACS Publications
Vesicle-shaped supramolecular polymers are formed by self-assembly of a DNA duplex
containing phenanthrene overhangs at both ends. In the presence of spermine, the …
containing phenanthrene overhangs at both ends. In the presence of spermine, the …
A simple molecular rotor for defining nucleoside environment within a DNA aptamer–protein complex
TZ Cservenyi, AJ Van Riesen, FD Berger… - ACS chemical …, 2016 - ACS Publications
The simple 5-furyl-2′-deoxyuridine (FurdU) nucleobase exhibits dual probing
characteristics displaying emissive sensitivity to changes in microenvironment polarity and …
characteristics displaying emissive sensitivity to changes in microenvironment polarity and …
Formation of Two Homo‐chromophoric H‐Aggregates in DNA‐Assembled Alternating Dye Stacks
CB Winiger, SM Langenegger, G Calzaferri… - Angewandte …, 2015 - Wiley Online Library
The understanding and description of collectively excited multichromophores is of crucial
importance for many areas of basic and applied research. DNA has been used for the …
importance for many areas of basic and applied research. DNA has been used for the …