The global prevalence of oral leukoplakia: a systematic review and meta-analysis from 1996 to 2022

C Zhang, B Li, X Zeng, XS Hu, H Hua - BMC Oral Health, 2023 - Springer
Background Oral leukoplakia (OLK) is a common oral potentially malignant disorder. The
global prevalence of solely OLK was published in 2003, while the prevalence varied among …

Specific Oral Microbial Differences in Proteobacteria and Bacteroidetes Are Associated with Distinct Sites When Moving from Healthy Mucosa to Oral Dysplasia—A …

A Radaic, ER Shamir, K Jones, A Villa, NR Garud… - Microorganisms, 2023 - mdpi.com
Oral potentially malignant disorders (OPMDs) are a group of conditions that carry a risk of
oral squamous cell carcinoma (OSCC) development. Recent studies indicate that …

Architectural and cytological features of epithelial dysplasia associated with transformation risk

X Cai, J Zhang, H Zhang, X Zhou, Z Zhou, F Jing… - Oral …, 2024 - Wiley Online Library
Objectives This study explored associations between histological features of dysplasia and
malignant transformation, as well as genomic copy number alterations. Materials and …

Biomarkers of malignant transformation in oral leukoplakia: from bench to bedside

X Cai, J Zhang, H Zhang, T Li - Journal of Zhejiang University-SCIENCE B, 2023 - Springer
Oral leukoplakia is a common precursor lesion of oral squamous cell carcinoma, which
indicates a high potential of malignancy. The malignant transformation of oral leukoplakia …

Single-Cell RNA Sequencing Analysis for Oncogenic Mechanisms Underlying Oral Squamous Cell Carcinoma Carcinogenesis with Candida albicans Infection

YP Hsieh, YH Wu, SM Cheng, FK Lin… - International journal of …, 2022 - mdpi.com
Oral squamous cell carcinoma (OSCC) carcinogenesis involves heterogeneous tumor cells,
and the tumor microenvironment (TME) is highly complex with many different cell types …

[HTML][HTML] Development of a pathomics-based model for the prediction of malignant transformation in oral leukoplakia

X Cai, L Li, F Yu, R Guo, X Zhou, F Zhang… - Laboratory …, 2023 - Elsevier
Accurate prognostic stratification of oral leukoplakia (OLK) with risk of malignant
transformation into oral squamous cell carcinoma is crucial. We developed an objective and …

Copy number alterations predict development of OSCC from oral leukoplakia

X Cai, J Zhang, L Li, L Liu, M Tang… - Journal of Dental …, 2024 - journals.sagepub.com
Oral leukoplakia (OLK) is a common type of potentially malignant disorder. Early
identification of the malignancy potential leads to a better management of OLK and …

The upregulation of oncogenic miRNAs in swabbed samples obtained from oral premalignant and malignant lesions

SC Lin, CJ Liu, SH Ji, WW Hung, YC Liu… - Clinical Oral …, 2022 - Springer
Objectives Oncogenic miRNAs upregulated in OSCC play a range of versatile roles in oral
carcinogenesis. Oral potentially malignant disorders (OPMDs) are the antecedent lesions to …

Surgical protocols for oral leukoplakia and precancerous lesions across three different anatomic sites

CM Pedroso, ES do Santos, FA Alves… - Oral …, 2024 - Wiley Online Library
Objective This systematic review and meta‐analysis aimed to compare the risk of recurrence
and cancer progression after surgical treatment for oral potentially malignant disorders …

Is OLP potentially malignant? A clue from ZNF582 methylation

YW Chiu, YF Su, CC Yang, CJ Liu, YJ Chen… - Oral …, 2023 - Wiley Online Library
Objective Whether oral lichen planus (OLP) was potentially malignant remains controversial.
Here, we examined associations of ZNF582 methylation (ZNF582m) with OLP lesions …