The metabolism and role of free fatty acids in key physiological processes in insects of medical, veterinary and forensic importance

A Kaczmarek, M Boguś - PeerJ, 2021 - peerj.com
Insects are the most widespread group of organisms and more than one million species
have been described. These animals have significant ecological functions, for example they …

Lipid metabolism in insect disease vectors

KC Gondim, GC Atella, EG Pontes… - Insect biochemistry and …, 2018 - Elsevier
More than a third of the world population is at constant risk of contracting some insect-
transmitted disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease …

Deficiency of Brummer lipase disturbs lipid mobilization and locomotion, and impairs reproduction due to defects in the eggshell ultrastructure in the insect vector …

DS Arêdes, T Rios, LF Carvalho-Kelly, V Braz… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Rhodnius prolixus is a hematophagous insect, which feeds on large and infrequent blood
meals, and is a vector of trypanosomatids that cause Chagas disease. After feeding, lipids …

Insulin receptor deficiency reduces lipid synthesis and reproductive function in the insect Rhodnius prolixus

G Silva-Oliveira, IF De Paula, JM Medina… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Rhodnius prolixus, a vector of Chagas disease, is a hematophagous insect that feeds
exclusively on blood. Each blood meal is digested within the first fourteen days after feeding …

Integration of transcriptome and proteome reveals molecular mechanisms underlying stress responses of the cutworm, Spodoptera litura, exposed to different levels of …

J Chen, Y Guo, S Huang, H Zhan, M Zhang, J Wang… - Chemosphere, 2021 - Elsevier
Heavy metals are major environmental pollutants that affect organisms across different
trophic levels. Herbivorous insects play an important role in the bioaccumulation, and …

A fatty acid synthase gene (FASN3) from the integument tissue of Rhodnius prolixus contributes to cuticle water loss regulation

DE Moriconi, AB Dulbecco, MP Juarez… - Insect molecular …, 2019 - Wiley Online Library
Fatty acid synthase is a multifunctional enzyme involved in the formation of fatty acids.
Despite the role of fatty acids in cell signalling and energy metabolism, and as precursors to …

Knockdown of carnitine palmitoyltransferase I (CPT1) reduces fat body lipid mobilization and resistance to starvation in the insect vector Rhodnius prolixus

IF De Paula, S Santos-Araujo, D Majerowicz… - Frontiers in …, 2023 - frontiersin.org
The energy stored in fatty acids is essential for several critical activities of insects, such as
embryogenesis, oviposition, and flight. Rhodnius prolixus is an obligatory hematophagous …

Deciphering the role of Rhodnius prolixus CYP4G genes in straight and methyl‐branched hydrocarbon formation and in desiccation tolerance

AB Dulbecco, DE Moriconi, S Lynn… - Insect Molecular …, 2020 - Wiley Online Library
Insect cuticle hydrocarbons are involved primarily in waterproofing the cuticle, but also
participate in chemical communication and regulate the penetration of insecticides and …

Transcriptome Analysis of the Triatoma infestans (Hemiptera: Reduviidae) Integument

GM Calderón-Fernández, DE Moriconi… - Journal of medical …, 2017 - academic.oup.com
The insect integument, formed by the cuticle and the underlying epidermis, is essential for
insect fitness, regulation of lipid biosynthesis and storage, insect growth and feeding …

Silencing of mitochondrial trifunctional protein A subunit (HADHA) increases lipid stores, and reduces oviposition and flight capacity in the vector insect Rhodnius …

DS Arêdes, IF De Paula, S Santos-Araujo… - Frontiers in Insect …, 2022 - frontiersin.org
Rhodnius prolixus is an obligatory hematophagous insect, vector of Chagas disease. After
blood meal, lipids are absorbed, metabolized, synthesized, and accumulated in the fat body …